American Journal of Ophthalmology
Volume 137, Issue 2 , Pages 373-375, February 2004

Responsiveness of the SF-36 health survey to changes in visual acuity among patients with subfoveal choroidal neovascularization☆

  • Ashley L. Childs, MS

      Affiliations

    • The Wilmer Ophthalmological Institute, The Johns Hopkins University, Baltimore, Maryland, USA (A.L.C.)
    • Corresponding Author InformationInquiries to Ashley L. Childs, MS, SST Coordinating Center, Wilmer Clinical Trials and Biometry, The Johns Hopkins University, 550 N. Broadway, 9th Floor, Baltimore, MD 21205-2010, USA. fax: (410) 955-0569
    • ,
  • the Submacular Surgery Trials Patient-Centered Outcomes Subcommittee* for the Submacular Surgery Trials Pilot Study Investigators**

Accepted 31 July 2003.

Abstract 

Purpose

To report the responsiveness of the SF-36 Health Survey to changes in visual acuity among patients with subfoveal choroidal neovascularization participating in the Submacular Surgery Trials pilot study.

Design

Cohort study.

Methods

Correlation analyses were used to explore relationships at each time point, and linear regression was used to determine the relation between the 2-year changes in SF-36 scores and visual acuity.

Results

A weak, but statistically significant, association was found between the 2-year changes in both the Physical Component Summary score and the Physical Functioning subscale with changes in visual acuity of the better eye. No association was found between changes in visual acuity and the Mental Component Summary score or the Mental Health subscale.

Conclusions

The SF-36 summary scales and the individual subscales were minimally responsive to 2-year changes in visual acuity in this subgroup of patients.

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  • * Other members of the subcommittee are: Carol M. Mangione, MD, MSPH (Chair); Eric B. Bass, MD, MPH (Co-Chair); Neil M. Bressler, MD; Li Ming Dong, PhD; Barbara S. Hawkins, PhD; Marta J. Marsh, MS; Päivi H. Miskala, PhD
  • ** A listing of all Submacular Surgery Trials Pilot Study investigators and personnel, as well as funding for the Submacular Surgery Trials Pilot Study, appears in: Submacular Surgery Trials Pilot Study Investigators. Submacular Surgery Trials (SST) randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration. I. Ophthalmic outcomes. SST Pilot Study Report Number 1. Am J Ophthalmol 2000;130:387–407.

☆ Funding for the Submacular Surgery Trials Pilot Study was provided through awards R21 EY10823 and U10 11547 from the National Eye Institute of the National Institutes of Health, Bethesda, Maryland, and by donations to the Submacular Surgery Trials Research Fund from Alcon, Ft. Worth, Texas; Altsheller-Durrell Foundation, Louisville, Kentucky; Baylor College, Department of Ophthalmology, Houston, Texas; Cleveland Clinic Foundation, Cleveland, Ohio; Duke Eye Center, Durham, North Carolina; Grieshaber and Company, Schaffhausen, Switzerland; Humana of Lexington, Lexington, Kentucky; Ohio State University, Department of Ophthalmology, Columbus, Ohio; Presbyterian-St. Luke's Hospital, Chicago, Illinois; Research to Prevent Blindness, Inc., New York, New York; Retina Associates of Cleveland, Cleveland, Ohio; Retina Associates of Florida, Tampa, Florida; Retinal-Vitreous Consultants, Pittsburgh, Pennsylvania; Richardson Family Trust, Pittsburgh, Pennsylvania; Scheie Age-Related Macular Degeneration Research Fund, Philadelphia, Pennsylvania; Synergetics, Inc., St. Charles, Missouri; University of Miami, Department of Ophthalmology, Miami, Florida; William Beaumont Hospital, Royal Oak, Michigan; and the Wilmer Ophthalmological Institute's Clinical Trials and Biometry Research Fund, Macular Research Fund, and Vitreoretinal Gift Fund, Baltimore, Maryland.

PII: S0002-9394(03)00911-5

doi:10.1016/S0002-9394(03)00911-5

American Journal of Ophthalmology
Volume 137, Issue 2 , Pages 373-375, February 2004

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