American Journal of Ophthalmology
Volume 140, Issue 3 , Pages 446.e1-446.e11, September 2005

The Association Between Hypermetropia and Essential Hypertension

The interim analysis of this study enrolling 256 cases was presented orally at the 14th Congress of the European Society of Ophthalmology in 2003.

  • Koray Karadayi, MD

      Affiliations

    • Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
    • Corresponding Author InformationInquiries to Dr Koray Karadayı, Emin Onat sk 7/4, 34710 Moda-Istanbul, Turkey; fax: +90-216-302-5871
  • ,
  • Tugrul Akin, MD

      Affiliations

    • Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
  • ,
  • Ferda Ciftci, MD

      Affiliations

    • Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
  • ,
  • Cihan Top, MD

      Affiliations

    • Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
  • ,
  • Ozcan Keskin, MD

      Affiliations

    • Department of Emergency Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
  • ,
  • Ejder Kardesoglu, MD

      Affiliations

    • Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
  • ,
  • Ahmet Hamdi Bilge, MD

      Affiliations

    • Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey.

Accepted 25 March 2005. published online 28 June 2005.

Purpose

To explore the relationship between the refractive state of the eye and high blood pressure in a representative population.

Design

Case-control study.

Methods

Three hundred twenty-one patients with essential hypertension (mean age 53.9 ± 15.5 years) and 188 age-matched and sex-matched healthy control subjects (mean age 50.9 ± 7.3 years) from the same regional Health Maintenance Organization were consecutively included for the study (P > .05 for age and sex). The refractive state of the eyes was identified objectively by an autorefractometer and retinoscopic examination, recording the autorefractometer values. Spherical equivalents between −0.50 (included) and +0.50 (included) diopters were regarded as emmetropia. Values below or above this interval were regarded as either myopia or hypermetropia. Mean spherical equivalents of the groups were compared using independent samples t test; distributions of refraction were compared with χ2 test.

Results

The mean spherical equivalent of the patients with essential hypertension was +0.88 ± 1.34 diopters (range −3.75 to +6.38 diopters), whereas the mean spherical equivalent of the control subjects was −0.26 ± 1.12 diopters (range −5.00 to +3.38 diopters) (P < .0001). Whereas 61.4% of hypertensive patients were hypermetropic, 18.1% of normotensive patients were hypermetropic (P < .0001).

Conclusions

There is a strong association of essential arterial hypertension with hypermetropia, which has not been previously reported. Given the findings of this study, we recommend that patients who have hypermetropia and have had no recent systemic examination should at least have their blood pressure checked.

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PII: S0002-9394(05)00422-8

doi:10.1016/j.ajo.2005.03.071

American Journal of Ophthalmology
Volume 140, Issue 3 , Pages 446.e1-446.e11, September 2005