Comparison of Retinal Thickness Measurements Between Three-dimensional and Radial Scans on Spectral-Domain Optical Coherence Tomography
Accepted 6 April 2009. published online 03 June 2009.
Purpose
To compare retinal thickness (RT) measurements between traditional 6 radial line scans and three-dimensional (3D) scans using spectral-domain optical coherence tomography (SD-OCT).
Design
Prospective, consecutive case series.
Methods
Twenty eyes of 17 patients with macular diseases and 8 healthy subjects were scanned using 2 different methods (3D scan and 6 radial line scan) using 2 different SD-OCT devices (Topcon OCT-1000 [Topcon Inc, Paramus, New Jersey, USA] and Canon SPOCT [(Canon/Optopol Inc, Depew, New York, USA]) by an experienced OCT operator. In 16 eyes, the data of TD-OCT were also obtained for comparison. The RT in 9 regions based on Early Treatment Diabetic Retinopathy Study areas were analyzed and compared. Bland-Altman plots were used to evaluate agreement.
Results
In the eyes with macular diseases, there was no significant difference in the RT between 3D and 6 radial line scans except the center subfield (P = .011) on the Topcon OCT-1000, and inner inferior (P = .031) and outer nasal (P = .014) areas on the Canon SPOCT. In the healthy subjects, there was no significant difference between the different scans on both SD-OCT devices. The 95% limit of subjects was 3.2 to 30.6 μm and 16.7 to 28.3 μm in the eye with macular diseases on OCT-1000 and SPOCT, respectively, and 6.7 to 13.6 μm and 10.8 to 32.3 μm in healthy subjects on OCT-1000 and SPOCT, respectively.
Conclusions
Preliminary results suggest the RT obtained by the 2 different scan patterns, 3D scan and 6 radial line scan, did not differ significantly on SD-OCT.
Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio
Inquiries to Peter K. Kaiser, Digital OCT Reading Center, Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk i3, Cleveland, OH 44195
ABSTRACT