American Journal of Ophthalmology
Volume 133, Issue 2 , Pages 211-214 , February 2002

Verteporfin infusion-associated pain

  • Natalie Borodoker, BA

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • Richard F Spaide, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
    • Corresponding Author InformationReprint requests to Richard F. Spaide, MD, Vitreous-Retina-Macula Consultants of New York, 519 East 72nd Street, Suite 203, New York, NY USA 10021; fax: (212) 628-0698
  • ,
  • Leandro Maranan

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • Jane Murray

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • K.Bailey Freund, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • Jason S Slakter, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • John A Sorenson, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • Lawrence A Yannuzzi, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • David R Guyer, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA
  • ,
  • Yale L Fisher, MD

      Affiliations

    • Vitreous-Retina-Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York USA

,Accepted 9 October 2001.

References 

  1. Treatment of Age-related Macular Degeneration with Photodynamic Therapy Study Group . Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin. Arch Ophthalmol. 1999;117:1329–1345
  2. Fleiss JL. Statistical methods for rates and proportions, 2nd ed. New York: John Wiley and Sons; 1981;56–61.
  3. Miller JW, Walsh AW, Kramer M, et al. Photodynamic therapy of experimental choroidal neovascularization using lipoprotein-delivered benzoporphyrin. Arch Ophthalmol 1995;113:810–808.
  4. Allison BA, Pritchard PH, Levy JG. Evidence for low-density lipoprotein receptor-mediated uptake of benzoporphyrin derivative. Br J Cancer. 1994;69:833–839
  5. Kramer M, Miller JW, Michaud N, et al. Liposomal benzoporphyrin derivative verteporfin photodynamic therapy: selective treatment of choroidal neovascularization in monkeys. Ophthalmology 1996 Mar;103:427–438.
  6. Miller JW, Schmidt-Erfurth U, Sickenberg M, et al.  Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration (results of a single treatment in a phase 1 and 2 study). Arch Ophthalmol. 1999;117:1161–1173
  7. Schmidt-Erfurth U, Miller JW, Sickenberg M, et al.  Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration (results of retreatments in a phase 1 and 2 study). Arch Ophthalmol. 1999;117:1177–1187
  8. Hui YF, Cortes JE. Chest and back pain associated with a six-hour infusion of liposomal daunorubicin. Ann Pharmacol. 2000;34:810–811
  9. Johnson MD, Drew RH, Perfect JR. Chest discomfort associated with liposomal amphotericin B (report of three cases and review of the literature). Pharmacother. 1998;18:1053–1061
  10. Miyamoto K, Schultz E, Heath T, Mitchell MD, Albertine KH, Staub NC. Pulmonary intravascular macrophages and hemodynamic effects of liposomes in sheep. J Appl Physiol. 1988;64:1143–1152

 Supported by The Macula Foundation, Inc. The authors have no financial interest in any aspect of this study.

PII: S0002-9394(01)01341-1

American Journal of Ophthalmology
Volume 133, Issue 2 , Pages 211-214 , February 2002