American Journal of Ophthalmology
Volume 135, Issue 1 , Pages 55-63 , January 2003

A six-month randomized clinical trial comparing the intraocular pressure-lowering efficacy of bimatoprost and latanoprost in patients with ocular hypertension or glaucoma

  • Robert S. Noecker, MD

      Affiliations

    • University of Arizona (R.S.N.), Tucson, Arizona, USA
    • Corresponding Author InformationInquiries to Scott M. Whitcup, MD, 2525 Dupont Dr, Irvine, CA, 92612-1599 USA; fax: (714) 246-6756;
    • ,
  • Monte S. Dirks, MD

      Affiliations

    • Black Hills Regional Eye Institute (M.S.D.), Rapid City, South Dakota, USA
    • ,
  • Neil T. Choplin, MD

      Affiliations

    • Eye Care of San Diego (N.T.C.), San Diego, California, USA
    • ,
  • Paula Bernstein, MS

      Affiliations

    • Allergan, Inc. (P.B., A.L.B., S.M.W.), Irvine, California, USA
    • ,
  • Amy L. Batoosingh

      Affiliations

    • Allergan, Inc. (P.B., A.L.B., S.M.W.), Irvine, California, USA
    • ,
  • Scott M. Whitcup, MD

      Affiliations

    • Allergan, Inc. (P.B., A.L.B., S.M.W.), Irvine, California, USA
    • ,
  • The Bimatoprost/Latanoprost Study Group

,Accepted 19 August 2002.

Title About Type File Size
Supplementary data 1

Mean (±SEM) intraocular pressure (IOP) at all measurements over the course of the study. Top: 8AM; Middle: 12PM; Bottom: 4PM. Baseline mean IOPs were 25.0 ± .24 mm Hg for bimatoprost and 24.9 ± .23 mm Hg for latanoprost (P=.641) at 8AM, 24.0 ± .27 mm Hg for bimatoprost and 23.3 ± .27 mm Hg for latanoprost (P=.028) at 12 PM and 22.6 ± .28 mm Hg for bimatoprost and 22.5 ± .27 mm Hg for latanoprost (P=.529) at 4PM. All mean IOPs are significantly lower in the bimatoprost treatment group than in the latanoprost treatment group at all follow-up study visits for all three timepoints, despite the higher baseline IOP at 12 PM in the bimatoprost treatment group.

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Supplementary data 2

Table of All IOP Measurements: mm Hg (SEMs).

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☆ This study was supported by Allergan, Inc. Paula Bernstein, Amy L. Batoosingh, and Scott M. Whitcup are employees of Allergan, Inc.InternetAdvance publication at ajo.com Oct 1, 2002.

PII: S0002-9394(02)01827-5

American Journal of Ophthalmology
Volume 135, Issue 1 , Pages 55-63 , January 2003

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