American Journal of Ophthalmology
Volume 137, Issue 1 , Pages 77-83 , January 2004

Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial

  • THE OPTIC NEURITIS STUDY GROUP

      Affiliations

    • Corresponding Author InformationInquiries to Robin L. Gal, MSPH, Optic Neuritis Study Group Coordinating Center, Jaeb Center for Health Research, 15310 Amberly Dr, Suite 350, Tampa, FL 33647, USA; fax: (813) 975-8761
    • The writing committee, investigators, and coordinators who participated in the study are listed in the Appendix.
    • Corresponding Author InformationInquiries to Robin L. Gal, MSPH, Optic Neuritis Study Group Coordinating Center, Jaeb Center for Health Research, 15310 Amberly Dr, Suite 350, Tampa, FL 33647, USA; fax: (813) 975-8761
    • ontt@jaeb.org

,Accepted 15 July 2003.

References 

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  2. Beck RW, Cleary PA, Anderson MM, et al.  A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. N Engl J Med. 1992;326:581–588
  3. Beck RW, Cleary PA, Trobe JD, et al.  The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis. N Engl J Med. 1993;329:1764–1769
  4. Cleary PA, Beck RW, Anderson MM, et al.  Design, methods, and conduct of the Optic Neuritis Treatment Trial. Control Clin Trials. 1993;14:123–142
  5. Optic Neuritis Study Group . The clinical profile of acute optic neuritis. Experience of the Optic Neuritis Treatment Trial. Arch Ophthalmol. 1991;109:1673–1678
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  8. Mangione CM, Lee PP, Gutierrez P, et al.  Development of the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25). Arch Ophthal. 2001;119:1050–1058
  9. Bradley WG, Whitty CWM. Acute optic neuritis (prognosis for development of multiple sclerosis). J Neurol Neurosurg Psychiatry. 1968;31:10–18
  10. Cohen M, Lessell S, Wolf P. A prospective study of the risk of developing multiple sclerosis in uncomplicated optic neuritis. Neurology. 1979;29:208–213
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  12. Rodriguez M, Siva A, Cross SA, O'Brien PC, Kurland LT. Optic neuritis (a population-based study in Olmsted County, Minnesota). Neurology. 1995;45:244–250
  13. Kurtzke JF. Rating neurologic impairment in multiple sclerosis (An expanded disability status scale (EDSS)). Neurology. 1983;33:1444–1452

 This study was supported by a Cooperative Agreement (U10 EY09435) from the National Eye Institute, National Institutes of Health.

PII: S0002-9394(03)00862-6

doi: 10.1016/S0002-9394(03)00862-6

American Journal of Ophthalmology
Volume 137, Issue 1 , Pages 77-83 , January 2004