American Journal of Ophthalmology
Volume 137, Issue 2 , Pages 228-235 , February 2004

Identifying early glaucoma with optical coherence tomography

Presented as a poster at the annual ARVO meeting, May 4–8, 2003, Fort Lauderdale, Florida.

  • Kouros Nouri-Mahdavi, MD

      Affiliations

    • Glaucoma Division, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA
  • ,
  • Douglas Hoffman, BA

      Affiliations

    • Glaucoma Division, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA
  • ,
  • Dana P. Tannenbaum, MD

      Affiliations

    • Glaucoma Division, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA
  • ,
  • Simon K. Law, MD PharmD

      Affiliations

    • Glaucoma Division, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA
  • ,
  • Joseph Caprioli, MD

      Affiliations

    • Glaucoma Division, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California, USA
    • Corresponding Author InformationInquiries to Joseph Caprioli, MD, Glaucoma Division, Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, CA 90095, USA; fax: (310) 206-7773

,Accepted 2 September 2003.

References 

  1. Puliafito CA, Hee MR, Lin CP, et al.  Imaging of macular diseases with optical coherence tomography. Ophthalmology. 1995;102:217–229
  2. Ripandelli G, Coppe AM, Capaldo A, Stirpe M. Optical coherence tomography. Semin Ophthalmol. 1998;13:199–202
  3. Baumal CR. Clinical applications of optical coherence tomography. Curr Opin Ophthalmol. 1999;10:182–188
  4. Schuman JS, Hee MR, Puliafito CA, et al.  Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. Arch Ophthalmol. 1995;113:586–596
  5. Schuman JS, Pedut-Kloizman T, Hertzmark E, et al.  Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmology. 1996;103:1889–1898
  6. Blumenthal EZ, Williams JM, Weinreb RN, Girkin CA, Berry CC, Zangwill LM. Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography. Ophthalmology. 2000;107:2278–2282
  7. Carpineto P, Ciancaglini M, Zuppardi E, Falconio G, Doronzo E, Mastropasqua L. Reliability of nerve fiber layer thickness measurements using optical coherence tomography in normal and glaucomatous eyes. Ophthalmology. 2003;110:190–195
  8. Bowd C, Zangwill LM, Berry CC, et al.  Detecting early glaucoma by assessment of retinal nerve fiber layer thickness and visual function. Invest Ophthalmol Vis Sci. 2001;42:1993–2003
  9. Greaney MJ, Hoffman DC, Garway-Heath DF, Nakla M, Coleman AL, Caprioli J. Comparison of optic nerve imaging methods to distinguish normal eyes from those with glaucoma. Invest Ophthalmol Vis Sci. 2002;43:140–145
  10. Kanamori A, Nakamura M, Escano MF, Seya R, Maeda H, Negi A. Evaluation of the glaucomatous damage on retinal nerve fiber layer thickness measured by optical coherence tomography. Am J Ophthalmol. 2003;135:513–520
  11. Mistlberger A, Liebmann JM, Greenfield DS, et al.  Heidelberg retina tomography and optical coherence tomography in normal, ocular-hypertensive, and glaucomatous eyes. Ophthalmology. 1999;106:2027–2032
  12. Hoh ST, Greenfield DS, Mistlberger A, Liebmann JM, Ishikawa H, Ritch R. Optical coherence tomography and scanning laser polarimetry in normal, ocular hypertensive, and glaucomatous eyes. Am J Ophthalmol. 2000;129:129–135
  13. Bowd C, Weinreb RN, Williams JM, Zangwill LM. The retinal nerve fiber layer thickness in ocular hypertensive, normal, and glaucomatous eyes with optical coherence tomography. Arch Ophthalmol. 2000;118:22–26
  14. Zangwill LM, Bowd C, Berry CC, et al.  Discriminating between normal and glaucomatous eyes using the Heidelberg retina tomograph, GDx nerve fiber analyzer, and optical coherence tomograph. Arch Ophthalmol. 2001;119:985–993
  15. Guedes V, Schuman JS, Hertzmark E, et al.  Optical coherence tomography measurement of macular and nerve fiber layer thickness in normal and glaucomatous human eyes. Ophthalmology. 2003;110:177–189
  16. Hee MR, Izatt JA, Swanson EA, et al.  Optical coherence tomography of the human retina. Arch Ophthalmol. 1995;113:325–332
  17. Schuman JS, Hee MR, Arya AV, et al.  Optical coherence tomography (A new tool for glaucoma diagnosis). Curr Opin Ophthalmol. 1995;6:89–95
  18. DeLong EDD, Clarke-Pearson D. Comparing the areas under two or more correlated operating characteristic curves (A nonparametric approach). Biometrics. 1988;44:837–845
  19. Perneger T. What's wrong with Bonferroni adjustments. Br Med J. 1998;316:1236–1238
  20. Mistlberger A, Liebmann JM, Greenfield DS, et al.  Assessment of optic disc anatomy and nerve fiber layer thickness in ocular hypertensive subjects with normal short-wavelength automated perimetry. Ophthalmology. 2002;109:1362–1366
  21. Mok KH, Lee VW, So KF. Retinal nerve fiber layer measurement by optical coherence tomography in glaucoma suspects with short-wavelength perimetry abnormalities. J Glaucoma. 2003;12:45–49

 Biosketches and/or additional material at www.ajo.com doi:10.1016/j.ajo.2003.09.004Supported by a grant from “Research to Prevent Blindness” and NIH-ROI EY12738.

PII: S0002-9394(03)01077-8

doi: 10.1016/j.ajo.2003.09.004

American Journal of Ophthalmology
Volume 137, Issue 2 , Pages 228-235 , February 2004