American Journal of Ophthalmology
Volume 137, Issue 3 , Pages 407-414 , March 2004

Optic radiation involvement in optic pathway gliomas in neurofibromatosis

  • Grant T. Liu, MD

      Affiliations

    • service of Neuro-ophthalmology (G.T.L.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • Corresponding Author InformationInquiries to Grant T. Liu, MD, Division of Neuro-ophthalmology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA; fax: (215) 349-5579
    • ,
  • Michael C. Brodsky, MD

      Affiliations

    • service of Neuro-oncology (P.C.P., J.B., A.J.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • Peter C. Phillips, MD

      Affiliations

    • service of Pathology (J.C.G.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • Jean Belasco, MD

      Affiliations

    • service of Pathology (J.C.G.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • Anna Janss, MD, PhD

      Affiliations

    • service of Pathology (J.C.G.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • Jeffrey C. Golden, MD, PhD

      Affiliations

    • service of Neuro-radiology (L.L.B.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • Larissa L. Bilaniuk, MD

      Affiliations

    • service of Neurosurgery (A.-C.D., L.N.S.), Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    • ,
  • G.Timothy Burson, MD

      Affiliations

    • department of Ophthalmology (M.C.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA,
    • ,
  • Ann-Christine Duhaime, MD

      Affiliations

    • department of Neurosurgery (G.T.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    • ,
  • Leslie N. Sutton, MD

      Affiliations

    • department of Neurosurgery (G.T.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

,Accepted 24 September 2003.

References 

  1. Brown EW, Riccardi VM, Mawad M, et al.  MR imaging of optic pathways in patients with neurofibromatosis. Am J Neuroradiol. 1987;8:1031–1036
  2. Aoki S, Barkovich AJ, Nishimura K, et al.  Neurofibromatosis types 1 and 2 (cranial MR findings). Radiology. 1989;172:527–534
  3. Shah JR, Patkar DP, Pungavkar SA, Parmer H. Extensive gliomas of visual tract in a patient of neurofibromatosis-I. Indian J Pediatr. 2000;67:939–940
  4. Listernick R, Charrow J, Tomita T, Goldman S. Carboplatin therapy for optic pathway tumors in children with neurofibromatosis type-1. J Neuro-Oncology. 1999;45:185–190
  5. Kornreich L, Blaser S, Schwarz M, et al.  Optic pathway glioma (correlation of imaging findings with the presence of neurofibromatosis). Am J Neuroradiol. 2001;22:1963–1969
  6. Lewis RA, Gerson LP, Axelson KA, et al.  von Recklinghausen neurofibromatosis. II. Incidence of optic gliomata. Ophthalmology. 1984;91:929–935
  7. Korf BR. Malignancy in neurofibromatosis type 1. Oncologist. 2000;5:477–485
  8. Friedman JM, Birch P. An association between optic glioma and other tumours of the central nervous system in neurofibromatosis type 1. Neuropediatrics. 1997;28:131–132
  9. Balcer LJ, Liu GT, Heller G, et al.  Visual prognosis in children with neurofibromatosis type-1 and optic pathway gliomas. Am J Ophthalmol. 2001;131:442–445

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PII: S0002-9394(03)01143-7

doi: 10.1016/j.ajo.2003.09.055

American Journal of Ophthalmology
Volume 137, Issue 3 , Pages 407-414 , March 2004

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