American Journal of Ophthalmology
Volume 137, Issue 3 , Pages 459-464 , March 2004

Factor XII deficiency: A thrombophilic risk factor for retinal vein occlusion

  • Claudia Kuhli, MD

      Affiliations

    • Department of Ophthalmology (C.K., F.K., C.O., L.O.H.), Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany
    • Corresponding Author InformationInquiries to Claudia Kuhli, MD, Klinik für Augenheilkunde, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai7, 60590 Frankfurt am Main, Germany; fax: (+49) 69–6301–83090
    • ,
  • Inge Scharrer, MD

      Affiliations

    • Department of Internal Medicine (I.S.), Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany
    • ,
  • Frank Koch, MD

      Affiliations

    • Department of Ophthalmology (C.K., F.K., C.O., L.O.H.), Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany
    • ,
  • Christian Ohrloff, MD

      Affiliations

    • Department of Ophthalmology (C.K., F.K., C.O., L.O.H.), Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany
    • ,
  • Lars-Olof Hattenbach, MD

      Affiliations

    • Department of Ophthalmology (C.K., F.K., C.O., L.O.H.), Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany

,Accepted 7 October 2003.

References 

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  3. Hattenbach LO, Klais C, Scharrer I. Heparin cofactor II deficiency in central retinal vein occlusion. Acta Ophthalmol Scand. 1998;76:758–759
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  5. Kuhli C, Hattenbach LO, Scharrer I, Koch F, Ohrloff C. High Prevalence of resistance to APC in young patients with retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol. 2002;240:163–168
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  28. Ogasawara MS, Aoki K, Katano K, Ozaki Y, Suzumori K. Factor XII but not protein C, protein S, antithrombin III, or factor XIII is predictor of recurrent miscarriage. Fertil Steril. 2001;75:916–919
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  32. Halbmayer WM, Haushofer A, Schon R, et al.  The prevalence of moderate and severe FXII (Hageman factor) deficiency among the normal population (evaluation of the incidence of FXII deficiency among 300 healthy blood donors). Thromb Haemost. 1994;71:68–72

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doi: 10.1016/j.ajo.2003.10.024

American Journal of Ophthalmology
Volume 137, Issue 3 , Pages 459-464 , March 2004

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