American Journal of Ophthalmology
Volume 138, Issue 4 , Pages 543-546 , October 2004

Analysis of melanoma cell type in uveal melanoma following treatment failure

  • Devron H. Char, MD

      Affiliations

    • Tumori Foundation, San Francisco (D.H.C.); Department of Ophthalmology, Stanford University, Palo Alto (D.H.C.); Department of Pathology, University of California, San Francisco (T.M.); and the Department of Ophthalmology, University of California, San Francisco (J.B.C.), California. San Francisco (D.H.C.)
    • Stanford University (D.H.C.), Palo Alto
    • Corresponding Author InformationInquiries to Devron H. Char, MD, 45 Castro Street, Suite 309, San Francisco, CA 94114; fax (415) 522-0723
    • ,
  • Theodore Miller, MD

      Affiliations

    • University of California, San Francisco (T.M., J.B.C.), San Francisco, California, USA
    • ,
  • J. Brooks Crawford, MD

      Affiliations

    • University of California, San Francisco (T.M., J.B.C.), San Francisco, California, USA

,Accepted 30 April 2004.

References 

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  2. Goldberg SF , Miele ME , Hatta N , Quivey JM , Castro J . Melanoma metastasis suppression by chromosome 6 (evidence for a pathway regulated by CRSP3 and TXNIP) . Cancer Res . 2003;63:432–440
  3. Char DH . Ocular melanoma . Surg Clin North Am . 2003;83:245–274
  4. Harbour JW , Char DH , Kroll S , et al.  Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal melanoma . Ophthalmology . 1997;104:1785–1793
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  7. Bechrakis NE , Sehu KW , Lee WR , Damato BE , Foerster MH . Transformation of cell type in uveal melanomas (a quantitative histologic analysis) . Arch Ophthalmol . 2000;118:1406–1412
  8. El-Shabrawi Y , Ardjomand N , Radner H , Ardjomand N . MMP-9 is predominantly expressed in epithelioid and not spindle cell melanoma . J Pathol . 2001;194:201–206
  9. Coupland SE , Anastassiou G , Stang A , et al.  The prognostic value of cyclin D1, p53, and MDM2 protein expression in uveal melanoma . J Pathol . 2000;191:120–126
  10. Jay V , Yi Q , Hunter WS , Zielenska M . p53 expression in uveal malignant melanomas . Pathology (Phila) . 1996;28:306–308
  11. Seftor RE , Seftor EA , Hendrix MJ . Molecular role(s) for integrins in human melanoma invasion . Cancer Metastasis Rev . 1999;18:359–375
  12. Char DH , Kroll SM , Stoloff A , et al.  Cytomorphometry of uveal melanoma. Comparison of fine needle aspiration biopsy samples with histologic sections . Anal Quant Cytol Histol . 1991;13:293–299
  13. Char DH , Kroll SM , Miller T , Castro J , Quivey J . Irradiated uveal melanomas (cytopathologic correlation with prognosis) . Am J Ophthalmol . 1996;122:509–513
  14. Hadden PW , Hiscott PS , Damato BE . Histopathology of eyes enucleated after endoresection of choroidal melanoma . Ophthalmology . 2004;111:154–160

 Supported in part by a grant from the Tumori Foundation.

PII: S0002-9394(04)00508-2

doi: 10.1016/j.ajo.2004.04.070

American Journal of Ophthalmology
Volume 138, Issue 4 , Pages 543-546 , October 2004

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