American Journal of Ophthalmology
Volume 138, Issue 6 , Pages 970-977 , December 2004

Inter-eye difference in diabetic macular edema after unilateral intravitreal injection of triamcinolone acetonide

  • Jost B. Jonas, MD

      Affiliations

    • Department of Ophthalmology, Faculty of Clinical Medicine, Mannheim of the Ruprecht-Varls University, Heidelberg, Germany.
    • Corresponding Author InformationInquiries to Jost B. Jonas, MD, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany; fax: 49-621-383-3803
  • ,
  • Björn Harder, MD

      Affiliations

    • Department of Ophthalmology, Faculty of Clinical Medicine, Mannheim of the Ruprecht-Varls University, Heidelberg, Germany.
  • ,
  • Bernd A. Kamppeter, MD

      Affiliations

    • Department of Ophthalmology, Faculty of Clinical Medicine, Mannheim of the Ruprecht-Varls University, Heidelberg, Germany.

,Accepted 6 July 2004.

References 

  1. Early Treatment Diabetic Retinopathy Study Research Group . Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report number 1 . Arch Ophthalmol . 1985;103:1796–1806
  2. Early Treatment Diabetic Retinopathy Study Research Group . Early photocoagulation for diabetic retinopathy . Ophthalmology . 1991;98:766–785 ETDRS report number 9
  3. McDonald HR , Schatz H . Grid photocoagulation for diffuse macular edema . Retina . 1985;5:65–72
  4. Lee CM , Olk RJ . Modified grid laser photocoagulation for diffuse diabetic macular edema. Long-term visual results . Ophthalmology . 1991;98:1594–1602
  5. Jonas JB , Hayler JK , Söfker A , Panda-Jonas S . Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative diabetic retinopathy . Am J Ophthalmol . 2001;131:468–471
  6. Jonas JB , Söfker A . Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema . Am J Ophthalmol . 2001;132:425–427
  7. Martidis A , Duker JS , Greenberg PB , et al.   Intravitreal triamcinolone for refractory diabetic macular edema . Ophthalmology . 2002;109:920–927
  8. Jonas JB , Kreissig I , Söfker A , Degenring RF . Intravitreal injection of triamcinolone acetonide for diabetic macular edema . Arch Ophthalmol . 2003;121:57–61
  9. Massin P , Audren F , Haouchine B , et al.   Intravitreal triamcinolone acetonide for diabetic diffuse macular edema (preliminary results of a prospective controlled trial) . Ophthalmology . 2004;111:218–224 discussion 224–225
  10. Early Treatment Diabetic Retinopathy Study Research Group . Classification of diabetic retinopathy from fluorescein angiograms. ETDRS report number 11 . Ophthalmology . 1991;98:807–822
  11. Machemer R , Sugita G , Tano Y . Treatment of intraocular proliferations with intravitreal steroids . Trans Am Ophthalmol Soc . 1979;77:171–180
  12. McCuen BW , Bessler M , Tano Y , Chandler D , Machemer R . The lack of toxicity of intravitreally administered triamcinolone acetonide . Am J Ophthalmol . 1981;91:785–788
  13. Schindler RH , Chandler DB , Thresher R , Machemer R . The clearance of intravitreal triamcinolone acetonide . Am J Ophthalmol . 1982;93:415–417
  14. Ishibashi T , Miki K , Sorgente N , Patterson R , Ryan SJ . Effects of intravitreal administration of steroids on experimental subretinal neovascularization in the subhuman primate . Arch Ophthalmol . 1985;103:708–711
  15. Scholes GN , O’Brien WJ , Abrams GW , Kubicek MF . Clearance of triamcinolone from vitreous . Arch Ophthalmol . 1985;103:1567–1569
  16. Coats ML , Peyman GA . Intravitreal corticosteroids in the treatment of exogenous fungal endophthalmitis . Retina . 1992;12:46–51
  17. Machemer R . Five cases in which a depot steroid (hydrocortisone acetate and methylprednisolone acetate) was injected into the eye . Retina . 1996;16:166–167
  18. Jonas JB . Concentration of intravitreally applicated triamcinolone acetonide in aqueous humour . Br J Ophthalmol . 2002;86:1066
  19. Beer PM , Bakri SJ , Singh RJ , Liu W , Peters GB , Miller M . Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection . Ophthalmology . 2003;110:681–686
  20. Jonas JB . Intraocular availability of triamcinolone acetonide after intravitreal injection . Am J Ophthalmol . 2004;137:560–562
  21. Greenberg PB , Martidis A , Rogers AH , Duker JS , Reichel E . Intravitreal triamcinolone acetonide for macular oedema due to central retinal vein occlusion . Br J Ophthalmol . 2002;86:247–248
  22. Ip MS , Kumar KS . Intravitreous triamcinolone acetonide as treatment for macular edema from central retinal vein occlusion . Arch Ophthalmol . 2002;120:1217–1219
  23. Park CH , Jaffe GJ , Fekrat S . Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion . Am J Ophthalmol . 2003;136:419–425
  24. Chen SD , Lochhead J , Patel CK , Frith P . Intravitreal triamcinolone acetonide for ischaemic macular oedema caused by branch retinal vein occlusion . Br J Ophthalmol . 2004;88:154–155
  25. Jonas JB , Hayler JK , Söfker A , Panda-Jonas S . Regression of neovascular iris vessels by intravitreal injection of crystalline cortisone . J Glaucoma . 2001;10:284–287
  26. Benitez Del Castillo Sanchez JM , Garcia Sanchez J . Intravitreal injection of triamcinolone acetonide in non infectious uveitis . Arch Soc Esp Oftalmol . 2001;76:661–664
  27. Martidis A , Duker JS , Puliafito CA . Intravitreal triamcino-lone for refractory cystoid macular edema secondary to birdshot retinochoroidopathy . Arch Ophthalmol . 2001;119:1380–1383
  28. Young S , Larkin G , Branley M , Lightman S . Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis . Clin Experiment Ophthalmol . 2001;29:2–6
  29. Antcliff RJ , Spalton DJ , Stanford MR , Graham EM , ffytche TJ , Marshall J . Intravitreal triamcinolone for uveitic cystoid macular edema (an optical coherence tomography study) . Ophthalmology . 2001;108:765–772
  30. Benhamou N , Massin P , Haouchine B , Audren F , Tadayoni R , Gaudric A . Intravitreal triamcinolone for refractory pseudophakic macular edema . Am J Ophthalmol . 2003;135:246–249
  31. Conway MD , Canakis C , Livir-Rallatos C , Peyman GA . Intravitreal triamcinolone acetonide for refractory chronic pseudophakic cystoid macular edema . J Cataract Refract Surg . 2003;29:27–33
  32. Penfold PL , Gyory JF , Hunyor AB , Billson FA . Exudative macular degeneration and intravitreal triamcinolone. A pilot study . Aust NZ J Ophthalmol . 1995;23:293–298
  33. Danis RP , Ciulla TA , Pratt LM , Anliker W . Intravitreal triamcinolone acetonide in exudative age-related macular degeneration . Retina . 2000;20:244–250
  34. Gillies MC , Simpson JM , Luo W , et al.   A randomized clinical trial of a single dose of intravitreal triamcinolone acetonide for neovascular age-related macular degeneration (one-year results) . Arch Ophthalmol . 2003;121:667–673
  35. Jonas JB , Kreissig I , Hugger P , Sauder G , Panda-Jonas S , Degenring R . Intravitreal triamcinolone acetonide for exudative age-related macular degeneration . Br J Ophthalmol . 2003;87:462–468
  36. Spaide RF , Sorenson J , Maranan L . Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization . Ophthalmology . 2003;110:1517–1525
  37. Jonas JB , Akkoyun I , Budde WM , Kreissig I , Degenring RF . Intravitreal re-injection of triamcinolone for exudative age-related macular degeneration . Arch Ophthalmol . 2004;122:218–222
  38. Jonas JB , Degenring RF , Kreissig I , Friedemann T , Akkoyun I . Exudative age-related macular degeneration treated by intravitreal triamcinolone acetonide. A prospective comparative non-randomized study . Eye . 2004; Forthcoming
  39. Jonas JB , Kreissig I , Degenring RF . Factors influencing visual acuity after intravitreal triamcinolone acetonide as treatment of exudative age-related macular degeneration . Br J Ophthalmol . 2004; Forthcoming
  40. Jonas JB , Degenring R , Kamppeter B , Kreissig I , Akkoyun I . Duration of the effect of intravitreal triamcinolone acetonide as treatment of diffuse diabetic macular edema . Am J Ophthalmol . 2004; Forthcoming
  41. Jonas JB , Kreissig I , Degenring RF , Kamppeter B . Repeated intravitreal injection of triamcinolone acetonide for diffuse diabetic macular oedema . Br J Ophthalmol . 2004; Forthcoming
  42. Scott IU , Flynn HW , Rosenfeld PJ . Intravitreal triamcinolone acetonide for idiopathic cystoid macular edema . Am J Ophthalmol . 2003;136:737–739
  43. Wingate RJ , Beaumont PE . Intravitreal triamcinolone and elevated intraocular pressure . Aust N Z J Ophthalmol . 1999;27:431–432
  44. Jonas JB , Kreissig I , Degenring R . Intraocular pressure after intravitreal injection of triamcinolone acetonide . Br J Ophthalmol . 2003;87:24–27
  45. Jonas JB , Kreissig I , Degenring RF . Retinal complications of intravitreal injections of triamcinolone acetonide . Graef Arch Clin Exp Ophthalmol . 2004;242:184–185
  46. Lewis H , Abrams GW , Blumenkranz MS , Campo RV . Vitrectomy for diabetic macular traction and edema associated with posterior hyaloidal traction . Ophthalmology . 1992;99:753–759
  47. Moshfeghi DM , Kaiser PK , Scott IU , et al.   Acute endophthalmitis following intravitreal triamcinolone acetonide injection . Am J Ophthalmol . 2003;136:791–796
  48. Roth DB , Chieh J , Spirn MJ , Green SN , Yarian DL , Chaudhry NA . Noninfectious endophthalmitis associated with intravitreal triamcinolone injection . Arch Ophthalmol . 2003;121:1279–1282
  49. Gillies MC , Simpson JM , Billson FA , et al.   Safety of an intravitreal injection of triamcinolone (results from a randomized clinical trial) . Arch Ophthalmol . 2004;122:336–340
  50. Degenring R , Jonas JB . Serum levels of triamcinolone acetonide after intravitreal injection . Am J Ophthalmol . 2004;137:1142–1143

PII: S0002-9394(04)00848-7

doi: 10.1016/j.ajo.2004.07.007

American Journal of Ophthalmology
Volume 138, Issue 6 , Pages 970-977 , December 2004