American Journal of Ophthalmology
Volume 140, Issue 5 , Pages 808-813 , November 2005

Correlation Between Dry Eye and Rheumatoid Arthritis Activity

  • Miho Fujita, MD

      Affiliations

    • Department of Ophthalmology, Nippon Medical School, Tokyo, Japan
    • ,
  • Tsutomu Igarashi, MD, PhD

      Affiliations

    • Department of Ophthalmology, Nippon Medical School, Tokyo, Japan
    • Corresponding Author InformationInquiries to Tsutomu Igarashi, MD, PhD, Department of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan; fax: +81-3-5685-0988
    • ,
  • Toshiyuki Kurai, MD

      Affiliations

    • Department of Ophthalmology, Nippon Medical School, Tokyo, Japan
    • ,
  • Manabu Sakane, MD

      Affiliations

    • Department of Joint Disease and Rheumatism, Nippon Medical School, Tokyo, Japan
    • ,
  • Shinichi Yoshino, MD, PhD

      Affiliations

    • Department of Joint Disease and Rheumatism, Nippon Medical School, Tokyo, Japan
    • ,
  • Hiroshi Takahashi, MD, PhD

      Affiliations

    • Department of Ophthalmology, Nippon Medical School, Tokyo, Japan

,Accepted 9 May 2005.

References 

  1. Lemp M . In: Basic principles and classification of dry eye disorders . New York: Springer; 1992;p. 103–131
  2. Lemp MA . Report of the National Eye Institute/Industry Workshop on Clinical Trials in Dry Eyes . CLAO J . 1995;21:221–232
  3. Manthorpe R , Frost-Larsen K , Isager H , Prause JU . Sjögren’s syndrome (a review with emphasis on immunological features) . Allergy . 1981;36:139–153
  4. Fox RI , Howell FV , Bone RC , Michelson P . Primary Sjögren syndrome (clinical and immunopathologic features) . Semin Arthritis Rheum . 1984;14:77–105
  5. Fox RI . Sjögren’s syndrome (evolving therapies) . Expert Opin Investig Drugs . 2003;12:247–254
  6. Robin J , Dugel R . In: Immunologic disorders of the cornea and conjunctiva . New York: Churchill Livingstone; 1988;p. 533–537
  7. Lipsky P . In: Rheumatoid arthritis . New York: McGraw-Hill; 1991;p. 1437–1443
  8. Jabs D . In: Ocular manifestations of the rheumatic diseases . Philadelphia: JB Lippincott; 1992;p. 1–5
  9. Lansbury J . Quantitation of the activity of rheumatoid arthritis. I. A method for recording its systemic manifestations . Am J Med Sci . 1956;231:616–621
  10. Lansbury J . Numerical method of evaluating the status of rheumatoid arthritis . Ann Rheum Dis . 1958;17:101–107
  11. Arnett FC , Edworthy SM , Bloch DA , et al.   The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis . Arthritis Rheum . 1988;31:315–324
  12. 8th International Symposium on Sjögren’s Syndrome. Available at: http://info.fujita-hu.ac.jp/∼ktorikai/DiagCriteriaE.htm. Accessed Jul 26, 2005.
  13. Tsubota K . New approaches to dry-eye therapy . Int Ophthalmol Clin . 1994;34:115–128
  14. Tsubota K , Fujihara T , Kaido M , Mori A , Mimura M , Kato M . Dry eye and Meige’s syndrome . Br J Ophthalmol . 1997;81:439–442
  15. Shimazaki JaDERGiJ . Definition and criteria of dry eye . Ganka . 1995;37:765–770
  16. Hikichi T , Yoshida A , Fukui Y , et al.   Prevalence of dry eye in Japanese eye centers . Graefes Arch Clin Exp Ophthalmol . 1995;233:555–558
  17. Schaumberg DA , Sullivan DA , Buring JE , Dana MR . Prevalence of dry eye syndrome among US women . Am J Ophthalmol . 2003;136:318–326
  18. Moss SE , Klein R , Klein BE . Incidence of dry eye in an older population . Arch Ophthalmol . 2004;122:369–373
  19. Mody GM , Hill JC , Meyers OL . Keratoconjunctivitis sicca in rheumatoid arthritis . Clin Rheumatol . 1988;7:237–241
  20. Ausayakhun S , Louthrenoo W , Aupapong S . Ocular diseases in patients with rheumatic diseases . J Med Assoc Thai . 2002;85:855–862
  21. Mokudai Y , Watanabe M , Fukushima A , et al.   Keratoconjunctivitis sicca in patients with rheumatoid arthritis . Nihon Ganka Kiyo . 1998;49:582–585
  22. Shimmura S , Ono M , Shinozaki K , et al.   Sodium hyaluronate eyedrops in the treatment of dry eyes . Br J Ophthalmol . 1995;79:1007–1011
  23. Condon PI , McEwen CG , Wright M , Mackintosh G , Prescott RJ , McDonald C . Double blind, randomised, placebo controlled, crossover, multicentre study to determine the efficacy of a 0.1% (w/v) sodium hyaluronate solution (Fermavisc) in the treatment of dry eye syndrome . Br J Ophthalmol . 1999;83:1121–1124
  24. Papa V , Aragona P , Russo S , Di Bella A , Russo P , Milazzo G . Comparison of hypotonic and isotonic solutions containing sodium hyaluronate on the symptomatic treatment of dry eye patients . Ophthalmologica . 2001;215:124–127
  25. Aragona P , Di Stefano G , Ferreri F , Spinella R , Stilo A . Sodium hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjögren’s syndrome patients . Br J Ophthalmol . 2002;86:879–884
  26. Nichols KK , Nichols JJ , Mitchell GL . The lack of association between signs and symptoms in patients with dry eye disease . Cornea . 2004;23:762–770
  27. Tan EM . Antinuclear antibodies (diagnostic markers for autoimmune diseases and probes for cell biology) . Adv Immunol . 1989;44:93–151
  28. Ben-Chetrit E , Fischel R , Rubinow A . Anti-SSA/Ro and anti-SSB/La antibodies in serum and saliva of patients with Sjögren’s syndrome . Clin Rheumatol . 1993;12:471–474
  29. Tengner P , Halse AK , Haga HJ , Jonsson R , Wahren-Herlenius M . Detection of anti-Ro/SSA and anti-La/SSB autoantibody-producing cells in salivary glands from patients with Sjögren’s syndrome . Arthritis Rheum . 1998;41:2238–2248
  30. Toker E , Yavuz S , Direskeneli H . Anti-Ro/SSA and anti-La/SSB autoantibodies in the tear fluid of patients with Sjögren’s syndrome . Br J Ophthalmol . 2004;88:384–387
  31. Miossec P . Pro- and antiinflammatory cytokine balance in rheumatoid arthritis . Clin Exp Rheumatol . 1995;13(suppl 12):S13–S16
  32. Feldmann M , Brennan FM , Maini RN . Role of cytokines in rheumatoid arthritis . Annu Rev Immunol . 1996;14:397–440
  33. Prada J , Noelle B , Baatz H , Hartmann C , Pleyer U . Tumour necrosis factor alpha and interleukin 6 gene expression in keratocytes from patients with rheumatoid corneal ulcerations . Br J Ophthalmol . 2003;87:548–550
  34. Jones DT , Monroy D , Ji Z , Pflugfelder SC . Alterations of ocular surface gene expression in Sjögren’s syndrome . Adv Exp Med Biol . 1998;438:533–536
  35. Tishler M , Yaron I , Geyer O , Shirazi I , Naftaliev E , Yaron M . Elevated tear interleukin-6 levels in patients with Sjögren syndrome . Ophthalmology . 1998;105:2327–2329
  36. Solomon A , Dursun D , Liu Z , Xie Y , Macri A , Pflugfelder SC . Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease . Invest Ophthalmol Vis Sci . 2001;42:2283–2292

 See accompanying Editorial on page 898.M.F. and T.I. contributed equally to this work.

PII: S0002-9394(05)00604-5

doi: 10.1016/j.ajo.2005.05.025

American Journal of Ophthalmology
Volume 140, Issue 5 , Pages 808-813 , November 2005

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