Retinal Blood Flow and Macular Edema After Radial Optic Neurotomy for Central Retinal Vein Occlusion
Accepted 2 August 2005. published online 25 October 2005.
Refers to article:
Does Radial Optic Neurotomy Alter Retinal Blood Flow in Eyes With a Central Retinal Vein Occlusion?
, 17 October 2005
R. Keith Shuler, Sharon Fekrat
American Journal of Ophthalmology
January 2006 (Vol. 141, Issue 1, Pages 145-146) Full Text |
Full-Text PDF (41 KB)
Purpose
To determine the effect of radial optic neurotomy (RON) on retinal blood flow (RBF) and macular edema in eyes with a central retinal vein occlusion.
Design
Prospective interventional study.
Methods
Seven eyes of seven patients with central retinal vein occlusion underwent RON and vitrectomy and were followed for at least 6 months. The RBF was calculated from dye dilution curves of video fluorescein angiograms. The foveal thickness was determined by optical coherence tomography.
Results
At 1 week after surgery, the RBF was significantly reduced from 28.5 ± 5.4 to 21.1 ± 6.6 pixel2/s (P < .01). At 6 months after surgery, the RBF (26.0 ± 7.7 pixel2/s) was not significantly different from the preoperative RBF, although chorioretinal anastomoses were found in all seven eyes. The foveal thickness was significantly decreased from 711 ± 271 to 488 ± 182 μm (P = .03). The postoperative visual acuity was better than the preoperative visual acuity by two or more lines in three out of seven eyes, and was worse in two eyes.
Conclusions
Neither RON nor chorioretinal anastomoses improved the RBF but macular edema was improved. These findings suggest that removal of the vitreous could reduce macular edema as in diabetic macular edema. However, we cannot exclude the possibility that the changes represent the natural course of this disease.
Department of Ophthalmology, Fujita Health University School of Medicine, Aichi, Japan.
Inquiries to Naoichi Horio, MD, Department of Ophthalmology, Fujita Health University School of Medicine, 1-98 Toyoake, Aichi 470-1192, Japan; fax: 81-562-95-5177
ABSTRACT