American Journal of Ophthalmology
Volume 141, Issue 6 , Pages 1016-1021.e1 , June 2006

Smoking Associated With Damage to the Lipid Layer of the Ocular Surface

  • Dilek Dursun Altinors, MD

      Affiliations

    • Department of Ophthalmology, School of Medicine, Baskent University, Ankara, Turkey
    • Corresponding Author InformationInquiries to Dilek Dursun Altinors, MD, 10 Sok, No. 45, 06490, Bahcelievler, Ankara, Turkey
  • ,
  • Sezin Akça, MD

      Affiliations

    • Department of Ophthalmology, School of Medicine, Baskent University, Ankara, Turkey
  • ,
  • Yonca A. Akova, MD

      Affiliations

    • Department of Ophthalmology, School of Medicine, Baskent University, Ankara, Turkey
  • ,
  • Banu Bilezikçi, MD

      Affiliations

    • Department of Pathology, School of Medicine, Baskent University, Ankara, Turkey
  • ,
  • Eiki Goto, MD, PhD

      Affiliations

    • Keio University School of Medicine, Department of Ophthalmology, Tokyo, Japan.
  • ,
  • Murat Dogru, MD, PhD

      Affiliations

    • Keio University School of Medicine, Department of Ophthalmology, Tokyo, Japan.
  • ,
  • Kazuo Tsubota, MD, PhD

      Affiliations

    • Keio University School of Medicine, Department of Ophthalmology, Tokyo, Japan.

,Accepted 23 December 2005.

References 

  1. Chiba M , Masironi R . Toxic and trace elements in tobacco and tobacco smoke . Bull World Health Organ . 1992;70:270–276
  2. Cheng AC , Pang CP , Leung ATS , et al.   The association between cigarette smoking and ocular diseases . Hong Kong Med J . 2000;6:195–202
  3. Weber A . Annoyance and irritation by passive smoking . Prev Med . 1984;13:618–625
  4. Yoon KC , Song BY , Seo MS . Effects of smoking on tear film and ocular surface . Korean J Ophthalmol . 2005;19:18–22
  5. Oldigs M , Jorres R , Magnussen H . Acute effect of passive smoking on lung function and airway responsiveness in asthmatic children . Pediatr Pulmonol . 1991;10:123–131
  6. Solberg Y , Rosner M , Belkin M . The association between cigarette smoking and ocular diseases . Surv Ophthalmol . 1998;42:535–547
  7. Cometto Muniz JE , Cain WS . Sensory irritation (relation to indoor air pollution) . Ann N Y Acad Sci . 1992;641:137–151
  8. Yokoi N , Takehisa Y , Kinoshita S . Correlation of tear lipid layer interference patterns with the diagnosis and severity of dry eye . Am J Ophthalmol . 1996;122:818–824
  9. Caffery BE , Josephson JE . Corneal staining after sequential instillations of fluorescein over 30 days . Optom Vis Sci . 1991;68:467–469
  10. Nelson JD , Wright JC . Conjunctival goblet cell densities in ocular surface disease . Arch Ophthalmol . 1984;102:1049–1052
  11. Sullivan RM , Cermak JM , Papas AS , et al.   Economic and quality of life impact of dry eye symptoms in women with Sjögren’s syndrome . Adv Exp Med Biol . 2002;506:1183–1188
  12. Hirsch JD . Considerations in the pharmacoeconomics of dry eye . Manag Care . 2003;12:33–38
  13. Pflugfelder SC . Dry eye (the problem) . In:  Pflugfelder SC ,  Beuerman RW ,  Stern ME editor. Dry eye and ocular surface disorders . New York: Marcel Dekker; 2004;p. 1–5
  14. Lee DJ , LeBlanc W , Fleming LE , Gomez-Marin O , Pitman T . Trends in US smoking rates in occupational groups (the National Health Interview Survey 1987–1994) . J Occup Environ Med . 2004;46:538–548
  15. Duthie GG , Arthur JR , Beattie JAG , et al.   Cigarette smoking, antioxidants, lipid peroxidation, and coronary heart disease . Ann N Y Acad Sci . 1993;686:120–129
  16. Pryor WA . Cigarette smoke and the involvement of free radical reactions in chemical carcinogenesis . Br J Cancer . 1987;55:S19–S23
  17. Kirkham PA , Spooner G , Rahman I , Rossi AG . Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products . Biochim Biophys Res Commun . 2004;318:32–37
  18. Strong B , Farley W , Stern ME , Pflugfelder SC . Topical cyclosporine inhibits conjunctival epithelial apoptosis in experimental murine keratoconjunctivitis sicca . Cornea . 2005;24:80–85
  19. Gao J , Schwalb TA , Addeo JV , Ghosn CR , Stern ME . The role of apoptosis in the pathogenesis of canine keratoconjunctivitis sicca (the effect of topical cyclosporin A therapy) . Cornea . 1998;17:654–663
  20. Pre J , Le Floch A . Lipid peroxidation products and antioxidants in plasma of cigarette smokers . Clin Chem . 1990;36:1849–1850
  21. Durak I , Yalcin S , Cimen MYB , Buyukkocak S , Kacmaz M , Ozturk HS . Effects of smoking on plasma and erythrocyte anti-oxidant defense systems . J Toxicol Environ Health . 1999;56:373–378
  22. Weber A . Annoyance and irritation by passive smoking . Prev Med . 1984;13:615–618
  23. Stern ME . The normal tear film and ocular surface . In:  Pflugfelder SC ,  Beuerman RW ,  Stern ME editor. Dry eye and ocular surface disorders. Dry eye: the problem . New York: Marcel Dekker; 2004;p. 41–55
  24. Doane MG . Abnormalities of the structure of the superficial lipid layer on the in vivo dry-eye tear film . Adv Exp Med Biol . 1994;350:489–493
  25. Basu PK , Pimm PE , Shephard RJ , Silverman F . The effect of cigarette smoke on the human tear film . Can J Ophthalmol . 1978;13:22–26
  26. Wieslander G , Lindgren T , Norback D , Venge P . Changes in the ocular and nasal signs and symptoms of aircrew in relation to the ban on smoking on intercontinental flights . Scand J Work Environ Health . 2000;26:514–522
  27. van der Vaart H , Postma DS , Timens W , Ten Hacken NH . Acute effects of cigarette smoke on inflammation and oxidative stress (a review) . Thorax . 2004;59:713–721
  28. Grus FH , Sabuncuo P , Augustin A , Pfeiffer N . Effect of smoking on tear proteins . Graefe’s Arch Clin Exp Ophthalmol . 2002;240:889–892
  29. Delcourt C , Diaz JL , Ponton-Sanchez A , Papoz L . Smoking and age-related macular degeneration (the POLA Study (Pathologies Oculaires Liees a l’Age)) . Arch Ophthalmol . 1998;116:1031–1035
  30. Tamakoshi A , Yuzawa M , Matsui M , Uyama M , Fujiwara Nk , Ohno Y  Research Committee on Chorioretinal Degenerations . Smoking and neovascular form of age related macular degeneration in late middle aged males (findings from a case control study in Japan) . Br J Ophthalmol . 1997;81:901–904
  31. Suner IJ , Heidmann DE , Marin-Castano M , Hernandez EP , Pereira-Simon S , Cousins SW . Nicotine increases size and severity of experimental choroidal neovascularisation . Invest Ophthalmol Vis Sci . 2004;45:311–317

 Supported in part by Baskent University, Basic and Clinical Research Fund, and Department of Ophthalmology, Ankara, Turkey.

PII: S0002-9394(06)00020-1

doi: 10.1016/j.ajo.2005.12.047

American Journal of Ophthalmology
Volume 141, Issue 6 , Pages 1016-1021.e1 , June 2006