American Journal of Ophthalmology
Volume 141, Issue 6 , Pages 1009-1015.e1 , June 2006

Comparison of Corneal Nerve Regeneration and Sensitivity Between LASIK and Laser Epithelial Keratomileusis (LASEK)

  • Seung Jae Lee, MD

      Affiliations

    • Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
    • ,
  • Jin Kuk Kim, MD

      Affiliations

    • BS Balgensesang Ophthalmology Clinic, Seoul, Korea.
    • ,
  • Kyung Yul Seo, MD

      Affiliations

    • Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
    • ,
  • Eung Kweon Kim, MD, PhD

      Affiliations

    • Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
    • ,
  • Hyung Keun Lee, MD

      Affiliations

    • Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
    • Corresponding Author InformationInquiries to Hyung Keun Lee, MD, Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Yongdong Severance Hospital, 146-92 Dogok-Dong, Kangnam-Ku, Seoul, Korea

,Accepted 12 January 2006.

References 

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  2. Lee BH , McLaren JW , Erie JC , Hodge DO , Bourne WM . Reinnervation in the cornea after LASIK . Invest Ophthalmol Vis Sci . 2002;43:3660–3664
  3. Erie JC , Nau CB , McLaren JW , Hodge DO , Bourne WM . Long-term keratocyte deficits in the corneal stroma after LASIK . Ophthalmology . 2004;111:1356–1361
  4. Reinstein DZ , Silverman RH , Sutton HFS , et al.   Very high frequency ultrasound corneal analysis identifies anatomic correlates of topical complications of lamellar refractive surgery (anatomic diagnosis in lamellar surgery) . Ophthalmology . 1999;106:474–482
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  12. Perez-Santonja JJ , Sakla JF , Cardona C , Chipont E , Alio J . Corneal sensitivity after photorefractive keratectomy and laser in situ keratomileusis for low myopia . Am J Ophthalmol . 1999;127:497–504
  13. Matsui H , Kumano Y , Zushi I , et al.   Corneal sensation after correction of myopia by photorefractive keratectomy and laser in situ keratomileusis . J Cataract Refract Surg . 2001;27:370–373
  14. Battat L , Macri A , Dursun D , Pflugfelder SC . Effect of laser in situ keratomileusis on tear production, clearance, and the ocular surface . Ophthalmology . 2001;108:1230–1235
  15. Toda I , Asano-Kato N , Komai-Hori Y , Tsubota K . Dry eye after laser in situ keratomileusis . Am J Ophthalmol . 2001;132:1–7
  16. Herrmann WA , Shah C , Gabler B , et al.   Corneal sensation after laser epithelial keratomileusis for the correction of myopia . Graefes Arch Clin Exp Ophthalmol . 2005;243:33–37
  17. Campos M , Herzog L , Garbus JJ , McDonnell PJ . Corneal sensitivity after photorefractive keratectomy . Am J Ophthalmol . 1992;114:51–54
  18. Lawrenson JG , Corbett MC , O’Brart DPS , Marshall J . Effect of beam variables on corneal sensitivity after excimer laser photorefractive keratectomy . Br J Ophthalmol . 1997;81:686–690
  19. Lee HK , Lee KS , Kim HC , Lee SH , Kim EK . Nerve growth factor concentration and implications in photorefractive keratectomy vs laser in situ keratomileusis . Am J Ophthalmol . 2005;139:965–971
  20. Moilanen JA , Vesaluoma MH , Muller LJ , Tervo TM . Long-term corneal morphology after PRK by in vivo confocal microscopy . Invest Ophthalmol Vis Sci . 2003;44:1064–1069
  21. Bron AJ . Diagnosis of dry eye . Surv Ophthalmol . 2001;45(suppl 2):S221–S226

 Supported in part by a grant from the Korea Health 21 R&D project, Ministry of Health and Welfare, Republic of Korea (02-PJ1-PG1-CH02-0003).

PII: S0002-9394(06)00069-9

doi: 10.1016/j.ajo.2006.01.048

American Journal of Ophthalmology
Volume 141, Issue 6 , Pages 1009-1015.e1 , June 2006

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