American Journal of Ophthalmology
Volume 142, Issue 3 , Pages 456-463 , September 2006

The Role of High-Resolution Computed Tomography and Magnetic Resonance Imaging in the Evaluation of Isolated Orbital Neurofibromas

Presented in part as a poster at the annual meeting of the American Society of Ophthalmic Plastic Reconstructive Surgeons, Oct 23, 2004, New Orleans, Louisiana.

  • Won Chan Park, MD

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota
    • ,
  • W. Abraham White

      Affiliations

    • Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota
    • University of Missouri–Kansas City School of Medicine, Kansas City, Missouri
    • ,
  • John J. Woog, MD

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota
    • Corresponding Author InformationInquiries to John J. Woog, MD, Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905
    • ,
  • James A. Garrity, MD

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Yoon-Duck Kim, MD

      Affiliations

    • Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • John Lane, MD

      Affiliations

    • Department of Radiology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Robert Witte, MD

      Affiliations

    • Department of Radiology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Dusica Babovic-Vuksanovic, MD

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota

,Accepted 18 April 2006.

References 

  1. Levin LA , Jakobiec FA . Peripheral nerve sheath tumors of the orbit. Principles and practices of ophthalmology . In:  Albert DM ,  Jakobiec FA editor. Philadelphia, Pennsylvania: WB Saunders; 2000;p. 3156–3181
  2. Shields JA , Shields CL , Lieb WE , et al.   Multiple orbital neurofibromas unassociated with von Recklinghausen’s disease . Arch Ophthalmol . 1990;108:80–83
  3. Rasmussen SA , Friedman JM . NF1 gene and neurofibromatosis 1 . Am J Epidemiol . 2000;151:33–40
  4. Upadhyaya M , Osborn M , Cooper DN . Detection of NF1 mutations utilizing the protein truncation test (PTT) . Methods Mol Biol . 2003;217:315–327
  5. Henderson JW , Campbell RJ , Farrow GM . In: Orbital tumors . 3rd ed.. New York: Raven Press; 1994;p. 221–237
  6. Krohel GB , Rosenberg PN , Wright JE , et al.   Localized orbital neurofibromas . Am J Ophthalmol . 1985;100:458–464
  7. Carroll GS , Haik BG , Fleming JC , et al.   Peripheral nerve tumors of the orbit . Radiol Clin North Am . 1999;37:195–202 xi–xii
  8. Shields JA , Bakewell B , Augsburger JJ , et al.   Classification and incidence of space-occupying lesions of the orbit (a survey of 645 biopsies) . Arch Ophthalmol . 1984;102:1606–1611
  9. Kyprianou IG , Mantry S , Reuser T . Segmental neurofibromatosis . Eye . 2004;18:950–952
  10. De Potter P , Shields CL , Shields JA , et al.   The CT and MRI features of an unusual case of isolated orbital neurofibroma . Ophthalmol Plast Reconstr Surg . 1992;8:221–227

 Supported in part by an unrestricted grant from Research to Prevent Blindness Inc, New York, New York.

PII: S0002-9394(06)00557-5

doi: 10.1016/j.ajo.2006.04.060

American Journal of Ophthalmology
Volume 142, Issue 3 , Pages 456-463 , September 2006

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