American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 539.e1-539.e13, October 2006

Changes in Visual Acuity in a Population Over a 15-year Period: The Beaver Dam Eye Study

  • Ronald Klein, MD, MPH

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • Corresponding Author InformationInquiries to Ronald Klein, MD, MPH, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, 610 North Walnut Street, 417 WARF, Madison, WI 53726-2336;
  • ,
  • Barbara E.K. Klein, MD, MPH

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
  • ,
  • Kristine E. Lee, MS

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
  • ,
  • Karen J. Cruickshanks, PhD

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
  • ,
  • Ronald E. Gangnon, PhD

      Affiliations

    • Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin

Accepted 2 June 2006. published online 14 July 2006.

Purpose

To describe the change in visual acuity in a 15-year period.

Design

Population-based study.

Methods

setting: Beaver Dam, Wisconsin. participants: 4068 persons 43 to 86 years of age at the time of a baseline examination in 1988 to 1990, and with follow-up examinations every five years thereafter. observation procedures: Best-corrected visual acuity after refraction, assessed by a modification of the ETDRS protocol. main outcome measure: Doubling of the visual angle; incidence of visual impairment.

Results

Eight percent of the population developed impaired vision (20/40 or worse), 0.8% developed severe visual impairment (20/200 or worse), 7% had doubling of the visual angle, and 2% had improved vision. People 75 years of age or older at baseline were more likely to develop impaired vision (odds ratio [OR] 12.8, 95% confidence interval [CI] 9.6 to 17.1, P < .001), doubling of the visual angle (OR 7.8, 95% CI 5.6 to 10.7, P < .001), and severe visual impairment (OR 20.6, 95% CI 9.5 to 44.8, P<0.001) compared with people younger than 75 years of age.

Conclusions

These data provide population-based estimates of the cumulative 15-year incidence of loss of vision over a wide spectrum of ages. In people 75 years of age or older the cumulative incidence of visual impairment accounting for the competing risk of death is 25%, of which 4% is severe, indicating a public health problem of considerable proportions as the US population in this age is expected to increase by 55% from 18 million in the year 2005 to 28 million by the year 2025.

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 Supported in part by National Institutes of Health Grant EY06594 (R.K., B.E.K.K.), and, in part, by Research to Prevent Blindness (R.K., B.E.K.K., Senior Scientific Investigator Award), New York, New York.

PII: S0002-9394(06)00675-1

doi:10.1016/j.ajo.2006.06.015

American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 539.e1-539.e13, October 2006