American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 597.e1-597.e5 , October 2006

Measurement of the Actual Dose of Triamcinolone Acetonide Delivered by Common Techniques of Intravitreal Injection

Presented in part at the Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, May 5, 2005, and at the American Society of Retina Specialists, Montreal, Canada, July 17, 2005.

,Accepted 18 May 2006.

References 

  1. Jonas JB , Kreissig I , Degenring RF . Intravitreal triamcinolone acetonide for treatment of intraocular proliferative, exudative, and neovascular diseases . Prog Retin Eye Res . 2005;24:587–611
  2. Spaide RF , Sorenson J , Maranan L . Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization . Ophthalmology . 2005;112:301–304
  3. Jonas JB , Kreissig I , Hugger P , Sauder G , Panda-Jonas S , Degenring RF . Intravitreal triamcinolone acetonide for exudative age-related macular degeneration . Br J Ophthalmol . 2003;87:462–468
  4. Jonas JB , Hayler JK , Sofker A , Panda-Jonas S . Regression of neovascular iris vessels by intravitreal injection of crystalline cortisone . J Glaucoma . 2001;10:284–287
  5. Scott IU , Ip MS . It’s time for a clinical trial to investigate intravitreal triamcinolone for macular edema due to retinal vein occlusion: the SCORE Study . Arch Ophthalmol . 2005;123:581–582
  6. Jonas JB , Degenring RF , Kreissig I , Akkoyun I , Kamppeter BA . Intraocular pressure elevation after intravitreal triamcinolone acetonide injection . Ophthalmology . 2005;112:593–598
  7. Smithen LM , Ober MD , Maranan L , Spaide RF . Intravitreal triamcinolone acetonide and intraocular pressure . Am J Ophthalmol . 2004;138:740–743
  8. Jonas JB , Degenring RF , Vossmerbauemer U , Kamppeter B . Frequency of cataract surgery after intravitreal injection of high-dosage triamcinolone acetonide . Eur J Ophthalmol . 2005;15:462–464
  9. Westfall AC , Osborn A , Kuhl D , Benz MS , Mieler WF , Holz ER . Acute endophthalmitis incidence: intravitreal triamcinolone . Arch Ophthalmol . 2005;123:1075–1077
  10. Sutter FK , Gillies MC . Pseudo-endophthalmitis after intravitreal injection of triamcinolone . Br J Ophthalmol . 2003;87:972–974
  11. Roth DB , Chieh J , Spirn MJ , Green SN , Yarian DL , Chaudhry NA . Noninfectious endophthalmitis associated with intravitreal triamcinolone injection . Arch Ophthalmol . 2003;121:1279–1282
  12. Parke DW . Intravitreal triamcinolone and endophthalmitis . Am J Ophthalmol . 2003;136:918–919
  13. Nelson ML , Tennant MT , Sivalingam A , Regillo CD , Belmont JB , Martidis A . Infectious and presumed noninfectious endophthalmitis after intravitreal triamcinolone acetonide injection . Retina . 2003;23:686–691
  14. Benz MS , Murray TG , Dubovy SR , Katz RS , Eifrig CW . Endophthalmitis caused by Mycobacterium chelonae abscessus after intravitreal injection of triamcinolone . Arch Ophthalmol . 2003;121:271–273
  15. Jonas JB , Kreissig I , Degenring RF . Endophthalmitis after intravitreal injection of triamcinolone acetonide . Arch Ophthalmol . 2003;121:1663–1664
  16. Moshfeghi DM , Kaiser PK , Scott IU , et al.   Acute endophthalmitis following intravitreal triamcinolone acetonide injection . Am J Ophthalmol . 2003;136:791–796
  17. Spandau UH , Derse M , Schmitz-Valckenberg P , Papoulis C , Jonas JB . Dosage dependency of intravitreal triamcinolone acetonide as treatment for diabetic macular oedema . Br J Ophthalmol . 2005;89:999–1003
  18. Spaide RF , Sorenson J , Maranan L . Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization . Ophthalmology . 2003;110:1517–1525
  19. Ciardella AP , Klancnik J , Schiff W , Barile G , Langton K , Chang S . Intravitreal triamcinolone for the treatment of refractory diabetic macular oedema with hard exudates: an optical coherence tomography study . Br J Ophthalmol . 2004;88:1131–1136
  20. Jonas JB , Kreissig I , Degenring RF . Intraocular pressure after intravitreal injection of triamcinolone acetonide . Br J Ophthalmol . 2003;87:24–27
  21. Jonas JB , Kreissig I , Sofker A , Degenring RF . Intravitreal injection of triamcinolone for diffuse diabetic macular edema . Arch Ophthalmol . 2003;121:57–61
  22. Garcia-Arumi J , Boixadera A , Giralt J , et al.   Comparison of different techniques for purification of triamcinolone acetonide suspension for intravitreal use . Br J Ophthalmol . 2005;89:1112–1114
  23. Rodriguez-Coleman H , Yuan P , Kim H , et al.   Intravitreal injection of triamcinolone for diffuse macular edema . Arch Ophthalmol . 2004;122:1085–1086 author reply 1086–1088
  24. Spandau UH , Derse M , Schmitz-Valckenberg P , et al.   Triamcinolone acetonide concentration after filtration of the solvent agent . Am J Ophthalmol . 2005;139:712–713
  25. Conway MD , Canakis C , Livir-Rallatos C , Peyman GA . Intravitreal traimcinolone acetonide for refractory chronic pseudophakic cystoid macular edema . J Cataract Refract Surg . 2003;29:27–33

 All fundings for this study came from internal sources.

PII: S0002-9394(06)00685-4

doi: 10.1016/j.ajo.2006.05.041

American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 597.e1-597.e5 , October 2006