American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 557-562 , October 2006

Evaluation of Lens Epithelial Cell Migration In Vivo at the Haptic-Optic Junction of a One-Piece Hydrophobic Acrylic Intraocular Lens

Presented in part at ESCRS, Paris, France, Sep 20, 2004.

  • Don R. Nixon, MD

      Affiliations

    • Trimed Eye Center, Barrie, Ontario, Canada
    • Corresponding Author InformationInquiries to Don R. Nixon, MD, Trimed Eye Center, 190 Cundles Road East, Suite 303, Barrie, Ontario, Canada L4M 4S5
    • ,
  • David J. Apple, MD

      Affiliations

    • Laboratories for Ophthalmic Device Research, Salt Lake City, Utah

,Accepted 21 May 2006.

References 

  1. Apple DJ , Peng Q , Visessook N , et al.   Eradication of posterior capsule opacification: documentation of a marked decrease in Nd:YAG laser posterior capsulotomy rates noted in an analysis of 5416 pseudophakic human eyes obtained postmortem . Ophthalmology . 2001;108:505–518
  2. Nishi O , Nishi K . Preventing posterior capsule opacification by creating a discontinuous sharp bend in the capsule . J Cataract Refract Surg . 1999;25:521–526
  3. Nishi O , Nishi K . Effect of the optic size of a single-piece acrylic intraocular lens on posterior capsule opacification . J Cataract Refract Surg . 2003;29:348–353
  4. Nishi O , Nishi K , Sakanishi K . Inhibition of migrating lens epithelial cells at the capsular bend created by the rectangular optic edge of a posterior chamber intraocular lens . Ophthalmic Surg Lasers . 1998;29:587–594
  5. Nishi O , Nishi K , Wickstrom K . Preventing lens epithelial cell migration using intraocular lenses with sharp rectangular edges . J Cataract Refract Surg . 2000;26:1543–1549
  6. Kruger AJ , Schauersberger J , Abela C , Schild G , Amon M . Two year results: sharp versus rounded optic edges on silicone lenses . J Cataract Refract Surg . 2000;26:566–570
  7. Buehl W , Menapace R , Sacu S , et al.   Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification . J Cataract Refract Surg . 2004;30:1661–1667
  8. Buehl W , Findl O , Menapace R , et al.   Long-term effect of optic edge design in an acrylic intraocular lens on posterior capsule opacification . J Cataract Refract Surg . 2005;31:954–961
  9. Sugita M , Kato S , Sugita G , Oshika T . Migration of lens epithelial cells through haptic root of single-piece acrylic-foldable intraocular lens . Am J Ophthalmol . 2004;137:377–379
  10. Werner L , Mamalis N , Pandey SK , et al.   Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge . J Cataract Refract Surg . 2004;30:2403–2409
  11. Werner L , Mamalis N , Izak AM , et al.   Posterior capsule opacification in rabbit eyes implanted with one-piece and three-piece hydrophobic acrylic intraocular lenses . J Cataract Refract Surg . 2005;31:805–811
  12. Nixon DR . In vivo digital imaging of the square-edged barrier effect of a silicone intraocular lens . J Cataract Refract Surg . 2004;30:2574–2584
  13. Wallin TR , Hinckley M , Nilson C , Olson RJ . A clinical comparison of single-piece and three-piece truncated hydrophobic acrylic intraocular lenses . Am J Ophthalmol . 2003;136:614–619
  14. Mian SI , Fahim K , Marcovitch A , et al.   Nd:YAG capsulotomy rates after use of the AcrySof acrylic three-piece and one-piece intraocular lenses . Br J Ophthalmol . 2005;89:1453–1457
  15. Ram J , Apple DJ , Peng Q , et al.   Update on fixation of rigid and foldable posterior chamber intraocular lenses: part 2—choosing the correct haptic fixation and intraocular lens design to help eradicate posterior capsule opacification . Ophthalmology . 1999;106:891–900
  16. Peng Q , Visessook N , Apple DJ , et al.   Surgical prevention of posterior capsule opacification: part 3—Intraocular lens optic barrier effect as a second line of defense . J Cataract Refract Surg . 2000;26:198–213
  17. Nishi O , Nishi K , Akura J , Nagata T . Effect of round-edged acrylic intraocular lenses on preventing posterior capsule opacification . J Cataract Refract Surg . 2001;27:608–613

 Supported in part by an unrestricted grant from Advanced Medical Optics Inc.

PII: S0002-9394(06)00704-5

doi: 10.1016/j.ajo.2006.05.049

American Journal of Ophthalmology
Volume 142, Issue 4 , Pages 557-562 , October 2006

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