American Journal of Ophthalmology
Volume 142, Issue 6 , Pages 923-930.e1 , December 2006

Baseline Factors Predictive of Incident Penetrating Keratoplasty in Keratoconus

  • Mae O. Gordon, PhD

      Affiliations

    • Division of Biostatistics and the Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri
    • ,
  • Karen Steger-May, MA

      Affiliations

    • Division of Biostatistics and the Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri
    • ,
  • Loretta Szczotka-Flynn, OD, MS

      Affiliations

    • Department of Ophthalmology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Colleen Riley, OD, MS

      Affiliations

    • Vistakon, Inc, Jacksonville, Florida
    • ,
  • Charlotte E. Joslin, OD

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Illinois College of Medicine at Chicago, Chicago, Illinois
    • ,
  • Barry A. Weissman, OD, PhD

      Affiliations

    • UCLA Jules Stein Eye Institute, Los Angeles, California
    • ,
  • Barbara A. Fink, OD, PhD

      Affiliations

    • The Ohio State University College of Optometry, Columbus, Ohio
    • ,
  • Timothy B. Edrington, OD, MS

      Affiliations

    • Southern California College of Optometry, Fullerton, California
    • ,
  • Harald E. Olafsson, OD

      Affiliations

    • University of Utah, John Moran Eye Center, Department of Ophthalmology, Salt Lake City, Utah.
    • ,
  • Karla Zadnik, OD, PhD

      Affiliations

    • The Ohio State University College of Optometry, Columbus, Ohio
    • Corresponding Author InformationInquiries to Karla Zadnik, OD, PhD, The Ohio State University College of Optometry, 338 West Tenth Avenue, Columbus, Ohio 43210
    • ,
  • Clek Study Group

,Accepted 21 July 2006.

References 

  1. Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol. 1984;28:293–322
  2. Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998;42:297–319
  3. The Australian Corneal Graft Registry. 1990 to 1992 report. Aust N Z J Ophthalmol. 1993;21:1–48
  4. Legeais JM, Parc C, d’Hermies F, et al. Nineteen years of penetrating keratoplasty in the Hotel-Dieu Hospital in Paris. Cornea. 2001;20:603–606
  5. Lois N, Kowal VO, Cohen EJ, et al. Indications for penetrating keratoplasty and associated procedures. Cornea. 1997;16:623–629
  6. Maeno A, Naor J, Lee HM, et al. Three decades of corneal transplantation: indications and patient characteristics. Cornea. 2000;19:7–11
  7. Dobbins KR, Price FWJ, Whitson WE. Trends in the indications for penetrating keratoplasty in the midwestern United States. Cornea. 2000;19:813–816
  8. 2004 Eye Banking Statistical Report. Eye Bank Association of America, 2005, Washington, DC.
  9. Crews MJ, Driebe WT, Stern GA. The clinical management of keratoconus: a 6 year retrospective study. CLAO J. 1994;20:194–197
  10. Kennedy RH, Bourne WM, Dyer JA. A 48-year clinical and epidemiologic study of keratoconus. Am J Ophthalmol. 1986;101:267–273
  11. Lass JH, Lembach RG, Park SB, et al. Clinical management of keratoconus (A multicenter analysis). Ophthalmology. 1990;97:433–445
  12. Smiddy WE, Hamburg TR, Kracher GP, Stark WJ. Keratoconus (Contact lens or keratoplasty?). Ophthalmology. 1988;95:487–492
  13. Sray WA, Cohen EJ, Rapuano CJ, Laibson PR. Factors associated with the need for penetrating keratoplasty in keratoconus. Cornea. 2002;21:784–786
  14. Tuft SJ, Moodaley LC, Gregory WM, et al. Prognostic factors for the progression of keratoconus. Ophthalmology. 1994;101:439–447
  15. Dana MR, Putz JL, Viana MAG, et al. Contact lens failure in keratoconus management. Ophthalmology. 1992;99:1187–1192
  16. Reeves SW, Stinnett S, Adelman RA, Afshari NA. Risk factors for progression to penetrating keratoplasty in patients with keratoconus. Am J Ophthalmol. 2005;607–611
  17. Belin MW, Fowler WG, Chambers WA. Keratoconus (Evaluation of recent trends in the surgical and nonsurgical correction of keratoconus). Ophthalmology. 1988;95:335–339
  18. Zadnik K, Barr JT, Edrington TB, et al. Baseline findings in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. Invest Ophthalmol Vis Sci. 1998;39:2537–2546
  19. Mandell RB. Keratoconus. In:  Mandell RB editors. Contact lens practice. Ed. 4.. Springfield, Ill: Charles C Thomas; 1988;p. 824–849
  20. Edrington TB, Barr JT, Zadnik K, et al. Standardized rigid contact lens fitting protocol for keratoconus. Optom Vis Sci. 1996;73:369–375
  21. Barr JT, Gordon MO, Zadnik K, et al. Photodocumentation of corneal scarring. J Refract Surg. 1996;12:492–500
  22. Pouliquen Y, Graf B, Hamada R, et al. Fibrocytes in keratoconus (Morphological aspect and modification of the extra-cellular space. Study with light and electron microscopy). Arch Ophthalmol Rev Gen Ophthalmol. 1972;32:571–586

 See accompanying Editorial on page 1044.

PII: S0002-9394(06)00866-X

doi: 10.1016/j.ajo.2006.07.026

American Journal of Ophthalmology
Volume 142, Issue 6 , Pages 923-930.e1 , December 2006

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