A Control-Matched Comparison of Laser Epithelial Keratomileusis and Laser In Situ Keratomileusis for Low to Moderate Myopia

Tobaigy, Faisal M.; Ghanem, Ramon C.; Sayegh, Rony R.; Hallak, Joelle A.; Azar, Dimitri T.

doi:10.1016/j.ajo.2006.08.001

« Previous Next »American Journal of Ophthalmology
Volume 142, Issue 6 , Pages 901-908, December 2006

A Control-Matched Comparison of Laser Epithelial Keratomileusis and Laser In Situ Keratomileusis for Low to Moderate Myopia

Faisal M. Tobaigy, MD
- Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts
Ramon C. Ghanem, MD
- Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts
- Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois.
Rony R. Sayegh, MD
- Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts
Joelle A. Hallak, BSc
- Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts
- Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois.
Dimitri T. Azar, MD
- Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and the Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts
- Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois.
- Inquiries to Dimitri T. Azar, MD, Chairman, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Illinois Eye and Ear Infirmary, Suite 2-50, 1855 W. Taylor Street, Chicago, IL 60612

Accepted 1 August 2006. published online 07 September 2006.

Purpose

To compare the visual and refractive outcomes of laser epithelial keratomileusis (LASEK) and laser in situ keratomileusis (LASIK) for the treatment of low to moderate myopia.

Design

Retrospective, nonrandomized, control-matched study.

Methods

The charts of 2257 eyes that underwent LASEK or LASIK treatment were reviewed. Patients who were 21 years of age or older having between −0.75 and −6.00 diopters (D) of myopia with up to −2.25 D of astigmatism were included. One hundred twenty-two LASEK-treated eyes were matched with 122 LASIK-treated eyes having preoperative spheres, cylinders, and spherical equivalent (SE) within ±0.50 D. Both groups had similar preoperative best spectacle-corrected visual acuity (BSCVA), laser platform, and follow-up durations. Outcome measures were visual and refractive results.

Results

Preoperatively, the mean SE was −3.50 ± 1.40 D for LASEK and −3.50 ± 1.42 D for LASIK (P = .59). Postoperatively, the mean logarithm of minimum angle of resolution (logMAR) uncorrected visual acuity (UCVA) was 0.01 ± 0.08 (20/21) for LASEK and 0.06 ± 0.12 (20/23) for LASIK; the mean SE was −0.15 ± 0.40 D for LASEK and −0.37 ± 0.45 D for LASIK; and the mean logMAR of BSCVA was −0.03 ± 0.06 (20/19) for LASEK and −0.02 ± 0.05 (20/19) for LASIK. No eye lost 2 or more lines of BSCVA in both groups.

Conclusions

Slight differences in the visual and refractive results between LASEK and LASIK were observed, despite the use of the same nomogram. Both procedures were safe, effective, and predictable. Nomogram adjustment may be necessary for LASIK surgeons adopting surface ablation.