American Journal of Ophthalmology
Volume 143, Issue 3 , Pages 409-415.e2 , March 2007

Impact of Dry Eye Syndrome on Vision-Related Quality of Life

  • Biljana Miljanović, MD, MPH, MSc

      Affiliations

    • Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
    • ,
  • Reza Dana, MD, MPH, MSc

      Affiliations

    • Schepens Eye Research Institute, Departments of Medicine and Ophthalmology, Harvard Medical School, Boston, Massachusetts.
    • ,
  • David A. Sullivan, PhD

      Affiliations

    • Schepens Eye Research Institute, Departments of Medicine and Ophthalmology, Harvard Medical School, Boston, Massachusetts.
    • ,
  • Debra A. Schaumberg, ScD, OD, MPH

      Affiliations

    • Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
    • Schepens Eye Research Institute, Departments of Medicine and Ophthalmology, Harvard Medical School, Boston, Massachusetts.
    • Corresponding Author InformationInquiries to Debra A. Schaumberg, ScD, OD, MPH, Division of Preventive Medicine, 900 Commonwealth Avenue East, Boston, MA 02215

,Accepted 22 November 2006.

References 

  1. Saaddine JB, Narayan KM, Vinicor F. Vision loss: a public health problem?. Ophthalmology. 2003;110:253–254
  2. Schaumberg DA, Buring JE, Sullivan DA, Dana MR. Hormone replacement therapy and dry eye syndrome. JAMA. 2001;286:2114–2119
  3. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003;136:318–326
  4. Schein OD, Munoz B, Tielsch JM, et al. Prevalence of dry eye among the elderly. Am J Ophthalmol. 1997;124:723–728
  5. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995;21:221–232
  6. Dalzell MD. Dry eye: prevalence, utilization, and economic implications. Manag Care. 2003;12:9–13
  7. Sullivan DA, Yamagami H, Liu M, et al. Sex steroids, the meibomian gland and evaporative dry eye. Adv Exp Med Biol. 2002;506:389–399
  8. Miljanovic B, Trivedi KA, Dana MR, et al. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr. 2005;82:887–893
  9. Albietz JM, Lenton LM, McLennan SG. Dry eye after LASIK: comparison of outcomes for Asian and Caucasian eyes. Clin Exp Optom. 2005;88:89–96
  10. Tsubota K, Nakamori K. Dry eyes and video display terminals. N Engl J Med. 1993;328:584
  11. Wolkoff P, Nojgaard JK, Troiano P, Piccoli B. Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking efficiency. Occup Environ Med. 2005;62:4–12
  12. Goto E, Yagi Y, Matsumoto Y, Tsubota K. Impaired functional visual acuity of dry eye patients. Am J Ophthalmol. 2002;133:181–186
  13. Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264–1268
  14. Moss SE, Klein R, Klein BE. Incidence of dry eye in an older population. Arch Ophthalmol. 2004;122:369–373
  15. Reddy P, Grad O, Rajagopalan K. The economic burden of dry eye: a conceptual framework and preliminary assessment. Cornea. 2004;23:751–761
  16. Mertzanis P, Abetz L, Rajagopalan K, et al. The relative burden of dry eye in patients’ lives: comparisons to a U.S. normative sample. Invest Ophthalmol Vis Sci. 2005;46:46–50
  17. Schiffman RM, Walt JG, Jacobsen G, et al. Utility assessment among patients with dry eye disease. Ophthalmology. 2003;110:1412–1419
  18. Rajagopalan K, Abetz L, Mertzanis P, et al. Comparing the discriminative validity of two generic and one disease-specific health-related quality of life measures in a sample of patients with dry eye. Value Health. 2005;8:168–174
  19. Cook NR, Lee IM, Gaziano JM, et al. Low-dose aspirin in the primary prevention of cancer: the Women’s Health Study: a randomized controlled trial. JAMA. 2005;294:47–55
  20. Ridker PM, Cook NR, Lee IM, et al. A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med. 2005;352:1293–1304
  21. Rexrode KM, Lee IM, Cook NR, et al. Baseline characteristics of participants in the Women’s Health Study. J Womens Health Gend Based Med. 2000;9:19–27
  22. Steering Committee of the Physicians’ Health Study Research Group. Final report on the aspirin component of the ongoing Physicians’ Health Study. N Engl J Med. 1989;321:129–135
  23. Hennekens CH, Buring JE, Manson JE, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996;334:1145–1149
  24. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177–188
  25. Sullivan RM, Cermak JM, Papas AS, et al. Economic and quality of life impact of dry eye symptoms in women with Sjogren’s syndrome. Adv Exp Med Biol. 2002;506:1183–1188
  26. Nichols KK, Mitchell GL, Zadnik K. Performance and repeatability of the NEI-VFQ-25 in patients with dry eye. Cornea. 2002;21:578–583
  27. Ishida R, Kojima T, Dogru M, et al. The application of a new continuous functional visual acuity measurement system in dry eye syndromes. Am J Ophthalmol. 2005;139:253–258
  28. Goto E, Yagi Y, Kaido M, et al. Improved functional visual acuity after punctal occlusion in dry eye patients. Am J Ophthalmol. 2003;135:704–705
  29. Begley CG, Himebaugh N, Renner D, et al. Tear break-up dynamics: a technique for quantifying tear film instability. Optom Vis Sci. 2006;83:15–21
  30. American Academy of Ophthalmology. Policy statement: Vision Requirements for Driving (c2001). 2006;Available at: http://www.aao.org/aao/member/policy/driving.cfm. Accessed Date: November 20
  31. Singh S, Perel M. Drivers’ perceptions of headlight glare from oncoming and following vehicles (DOT HS 809 669) (c2004). 2006;Available at: http://www-nrd.nhtsa.dot.gov/pdf/nrd-30/NCSA/Rpts/2003/809-669/images/GLARE_PERCEP.pdf. Accessed Date: November 20
  32. Huang FC, Tseng SH, Shih MH, Chen FK. Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes. Ophthalmology. 2002;109:1934–1940
  33. Statistics on the Aging Population [online database]. Department of Health and Human Services, Administration on Aging; 2006;http://www.aoa.gov/prof/Statistics/statistics.asp. Accessed Date: November 20.
  34. Bullough JD, Derlofske JV, Dee P, et al. An investigation of headlamp glare: intensity, spectrum and size. Washington, DC: National Highway Traffic Safety Administration NHTSA; 2003;Report No. DOT HS 809 692. :48. Available at: http://www-nrd.nhtsa.dot.gov/departments/nrd-01/GlareSpectrum/pages/TOC.html. Accessed Date: November 20, 2006.
  35. Rolando M, Iester M, Macri A, Calabria G. Low spatial-contrast sensitivity in dry eyes. Cornea. 1998;17:376–379
  36. Fan-Paul NI, Li J, Miller JS, Florakis GJ. Night vision disturbances after corneal refractive surgery. Surv Ophthalmol. 2002;47:533–546
  37. Gulati A, Sullivan R, Buring JE, et al. Validation and repeatability of a short questionnaire for dry eye syndrome. Am J Ophthalmol. 2006;142:125–131

PII: S0002-9394(06)01378-X

doi: 10.1016/j.ajo.2006.11.060

American Journal of Ophthalmology
Volume 143, Issue 3 , Pages 409-415.e2 , March 2007

Article Tools

* Image Usage & Resolution