American Journal of Ophthalmology
Volume 145, Issue 1 , Pages 29-36.e1, January 2008

Ten-year Follow-up of Photorefractive Keratectomy for Myopia of Less Than −6 Diopters

  • Jorge L. Alió

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
    • Corresponding Author InformationInquiries to Jorge L. Alió, Vissum-Instituto Oftalmológico de Alicante, Avda. De Denia s/n, 03016, Alicante, Spain
  • ,
  • Orkun Muftuoglu

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
    • Ankara University School of Medicine, Ankara, Turkey
  • ,
  • Dolores Ortiz

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
  • ,
  • Alberto Artola

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
  • ,
  • Juan J. Pérez-Santonja

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
  • ,
  • Gracia Castro de Luna

      Affiliations

    • Vissum-Instituto Oftalmológico de Almeria, Almeria, Spain.
  • ,
  • Sabat K. Abu-Mustafa

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain
  • ,
  • Maria Jose Garcia

      Affiliations

    • Vissum-Instituto Oftalmológico de Alicante and Division of Ophthalmology, Miguel Hernandez University Medical School, Alicante, Spain

Accepted 8 September 2007. published online 18 October 2007.

Purpose

To evaluate the long-term outcomes of excimer laser myopic photorefractive keratectomy (PRK) for myopia of less than −6 diopters (D).

Design

Long-term (10-year) follow-up retrospective, interventional case series.

Methods

The study included 225 eyes of 138 myopic patients with spherical equivalent (SE) between 0 and −6 D treated with myopic PRK at the Instituto Oftalmológico de Alicante, Alicante, Spain, using the VISX 20/20 excimer laser (Santa Clara, California, USA). The main outcome measures were refractive predictability and stability, mean corneal keratometry, topographical cylinder, safety, efficacy, stability of visual acuity, and postoperative complications.

Results

At 10 years, 169 (75%) of 225 eyes were within ± 1.00 D and 207 (92%) were within ± 2.00 D. Ninety-five (42%) eyes underwent retreatments because of overcorrection, regression, or both. The mean SE slightly decreased (myopic regression) with a mean magnitude of −0.10 ± 1.08 D over 10 years (−0.01 ± 0.11 D per year). Forty-one (58%) of 225 eyes demonstrated increase in best spectacle-corrected visual acuity after 10 years. Only one eye lost eight lines because of significant cataract, and two eyes lost vision (one lost seven lines and the other lost four lines) because of posterior segment-related complications. The mean corneal haze score gradually decreased from 0.22 ± 0.39 at three months to 0.01 ± 0.09 at 10 years.

Conclusions

Photorefractive keratectomy for myopia of less than −6 D is a safe and effective procedure in the long-term.

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 See accompanying Editorial on page 1.

PII: S0002-9394(07)00797-0

doi:10.1016/j.ajo.2007.09.007

Refers to article:

  • Have You Seen the 10-Year Long-term Safety Data on Laser In Situ Keratomileusis? , 19 November 2007

    George O. Waring
    American Journal of Ophthalmology January 2008 (Vol. 145, Issue 1, Pages 1-2)

American Journal of Ophthalmology
Volume 145, Issue 1 , Pages 29-36.e1, January 2008