American Journal of Ophthalmology
Volume 145, Issue 4 , Pages 611-617.e1 , April 2008

Changes in the Quality-of-Life of People with Keratoconus

  • Steven M. Kymes

      Affiliations

    • Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri
    • Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri
    • Center for Health Policy, Washington University, St Louis, Missouri
    • Corresponding Author InformationInquiries to Steven M. Kymes, Department of Ophthalmology and Visual Sciences, Washington University Medical School, Campus Box 8096, 660 South Euclid Avenue, St Louis, MO 63110
  • ,
  • Jeffrey J. Walline

      Affiliations

    • College of Optometry, The Ohio State University, Columbus, Ohio
  • ,
  • Karla Zadnik

      Affiliations

    • College of Optometry, The Ohio State University, Columbus, Ohio
  • ,
  • John Sterling

      Affiliations

    • Gunderson Clinic, La Crosse, Wisconsin.
  • ,
  • Mae O. Gordon

      Affiliations

    • Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri
    • Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri
  • ,
  • Collaborative Longitudinal Evaluation of Keratoconus Study Group

,Accepted 16 November 2007.

References 

  1. Kennedy RH, Bourne WM, Dyer JA. A 48-year clinical and epidemiologic study of keratoconus. Am J Ophthalmol. 1986;101:267–273
  2. Zadnik K, Barr JT, Edrington TB, et al. Baseline findings in the Collaborative Longitudnal Evaluation of Keratoconus (CLEK) Study. Invest Ophthalmol Vis Sci. 1998;39:2537–2546
  3. Gordon MO, Schechtman KB, Davis LJ, McMahon TT, Schornack J, Zadnik K. Visual acuity repeatability in keratoconus: impact on sample size (Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group). Optom Vis Sci. 1998;75:249–257
  4. Lass JH, Lembach RG, Park SB, et al. Clinical management of keratoconus (A multicenter analysis). Ophthalmology. 1990;97:433–445
  5. Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:714–720
  6. Age-Related Eye Disease Study Research Group. The Age-Related Eye Disease Study (AREDS): design implications. AREDS Report No. 1. Control Clin Trials. 1999;20:573–600
  7. Thalasselis A, Taie HF, Etchepareborda J, Selim A. Keratoconus, magnesium deficiency, type A behavior, and allergy. Am J Optom Physiol Opt. 1988;65:499–505
  8. Mangione CM, Berry S, Spritzer KL, et al. Identifying the content area for the 51-item National Eye Institute Visual Function Questionnaire: results from focus groups with visually impaired persons. Arch Ophthalmol. 1998;116:227–233
  9. Mangione CM, Lee PP, Gutierriez PR, Spritzer KL, Berry S, Hays RD. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol. 2001;119:1050–1058
  10. Mangione CM, Lee PP, Pitts J, Gutierriez PR, Berry S, Hays RD. Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ). Arch Ophthalmol. 1998;116:1496–1504
  11. Kymes SM, Walline JJ, Zadnik K, Gordon MO Collaborative Longitudinal Evaluation of Keratoconus Study Group. Quality-of-life in keratoconus. Am J Ophthalmol. 2004;138:527–535
  12. Lindblad AS, Clemons TE. Responsiveness of the National Eye Institute Visual Function Questionnaire to progression to advanced age-related macular degeneration, vision loss, and lens opacity: AREDS Report No. 14. Arch Ophthalmol. 2005;123:1207–1214
  13. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality-of-life: the remarkable universality of half a standard deviation. Med Care. 2003;41:582–592
  14. Hosmer DW, Lemeshow S. Applied logistic regression. In: 2nd ed.. New York, New York: John Wiley and Sons; 2000;p. 1–395
  15. Davis LJ, Schechtman KB, Wilson BS, et al. Longitudinal changes in visual acuity in keratoconus. Invest Ophthalmol Vis Sci. 2006;47:489–500
  16. McMahon TT, Edrington TB, Szczotka-Flynn L, et al. Longitudinal changes in corneal curvature in keratoconus. Cornea. 2006;25:296–305
  17. Brierly SC, Izquierdo L, Mannis MJ. Penetrating keratoplasty for keratoconus. Cornea. 2000;19:329–332
  18. Gordon MO, Steger-May K, Szczotka-Flynn L, et al. Baseline factors predictive of incident penetrating keratoplasty in keratoconus. [comment] Am J Ophthalmol. 2006;142:923–930

PII: S0002-9394(07)00987-7

doi: 10.1016/j.ajo.2007.11.017

American Journal of Ophthalmology
Volume 145, Issue 4 , Pages 611-617.e1 , April 2008