American Journal of Ophthalmology
Volume 146, Issue 2 , Pages 211-217.e1 , August 2008

Bevacizumab Pretreatment and Long-acting Gas Infusion on Vitreous Clear-up After Diabetic Vitrectomy

  • Chung-May Yang

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, and College of Medical, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationInquiries to Chung-May Yang, Department of Ophthalmology, National Taiwan University Hospital; College of Medicine, National Taiwan University, No. 7, Chung Shan South Road, Taipei, Taiwan
    • ,
  • Po-Ting Yeh

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, and College of Medical, National Taiwan University, Taipei, Taiwan
    • Department of Ophthalmology, En Chu Kong Hospital, Taipei, Taiwan.
    • ,
  • Chang-Hao Yang

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, and College of Medical, National Taiwan University, Taipei, Taiwan
    • ,
  • Muh-Shy Chen

      Affiliations

    • Department of Ophthalmology, National Taiwan University Hospital, and College of Medical, National Taiwan University, Taipei, Taiwan

,Accepted 15 April 2008.

References 

  1. Yang CM. Surgical treatment for diabetic retinopathy: 5-year experience. J Formos Med Assoc. 1998;97:477–484
  2. Schachat AP, Oyakawa RT, Michels RG, Rice TA. Complications of vitreous surgery for diabetic retinopathy (II. Postoperative complications). Ophthalmology. 1983;90:522–530
  3. Novak MA, Rice TA, Michels RG, Auer C. Vitreous hemorrhage after vitrectomy for diabetic retinopathy. Ophthalmology. 1984;91:1485–1489
  4. West JF, Gregor ZJ. Fibrovascular ingrowth and recurrent haemorrhage following diabetic vitrectomy. Br J Ophthalmol. 2000;84:822–825
  5. Bhende M, Agraharam SG, Gopal L, et al. Ultrasound biomicroscopy of sclerotomy sites after pars plana vitrectomy for diabetic vitreous hemorrhage. Ophthalmology. 2000;107:1729–1736
  6. Hershberger VS, Augsburger JJ, Hutchins RK, Raymond LA, Krug S. Fibrovascular ingrowth at sclerotomy sites in vitrectomized diabetic eyes with recurrent vitreous hemorrhage: ultrasound biomicroscopy findings. Ophthalmology. 2004;111:1215–1221
  7. Kreiger AE. Wound complications in pars plana vitrectomy. Retina. 1993;13:335–344
  8. Yeh PT, Yang CM, Yang CH, Huang JS. Cryotherapy of the anterior retina and sclerotomy sites in diabetic vitrectomy to prevent recurrent vitreous hemorrhage: an ultrasound biomicroscopy study. Ophthalmology. 2005;112:2095–2102
  9. Yang CM, Yeh PT, Yang CH. Intravitreal long-acting gas in the prevention of early postoperative vitreous hemorrhage in diabetic vitrectomy. Ophthalmology. 2007;114:710–715
  10. Oshima Y, Sakaguchi H, Gomi F, Tano Y. Regression of iris neovascularization after intravitreal injection of bevacizumab in patients with proliferative diabetic retinopathy. Am J Ophthalmol. 2006;142:155–158
  11. Avery RL. Regression of retinal and iris neovascularization after intravitreal bevacizumab (Avastin) treatment. Retina. 2006;26:352–354
  12. Avery RL, Pearlman J, Pieramici DJ, et al. Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology. 2006;113:1695–1705
  13. Eliott D, Lee MS, Abrams GS. Proliferative diabetic retinopathy: principles and techniques of surgical treatment. In:  Ryan SJ,  Hinton DR,  Schachat AP,  Wilkinson P editor. 4th ed.. Retina (Surgical Retina). Vol. 3:Philadelphia, Pennsylvania: Elsevier Mosby; 2006;p. 2413–2415
  14. Diabetic Retinopathy Vitrectomy Study Group. Two-year course of visual acuity in severe proliferative diabetic retinopathy with conventional management (Diabetic Retinopathy Vitrectomy Study (DRVS) Report No. 1). Ophthalmology. 1985;92:492–502
  15. Ramezani AR, Ahmadieh H, Ghaseminejad AK, Yazdani S, Golestan B. Effect of tranexamic acid on early postvitrectomy diabetic haemorrhage; a randomised clinical trial. Br J Ophthalmol. 2005;89:1041–1044
  16. Heiduschka P, Fietz H, Hofmeister S, et al. Penetration of bevacizumab through the retina after intravitreal injection in the monkey. Invest Ophthalmol Vis Sci. 2007;48:2814–2823
  17. Charles S, Rosenfeld PJ, Gayer S. Medical consequences of stopping anticoagulant therapy before intraocular surgery or intravitreal injections. Retina. 2007;27:813–815
  18. Mosesson MW. Fibrinogen and fibrin structure and functions. J Thromb Haemost. 2005;3:1894–1904
  19. Hirata A, Takano A, Inomata Y, Yonemura N, Sagara N, Tanihara H. Plasmin-assisted vitrectomy for management of proliferative membrane in proliferative diabetic retinopathy: a pilot study. Retina. 2007;27:1074–1078

PII: S0002-9394(08)00312-7

doi: 10.1016/j.ajo.2008.04.028

American Journal of Ophthalmology
Volume 146, Issue 2 , Pages 211-217.e1 , August 2008

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