American Journal of Ophthalmology
Volume 146, Issue 5 , Pages 664-673.e1 , November 2008

Implantable Telescope for End-Stage Age-related Macular Degeneration: Long-term Visual Acuity and Safety Outcomes

  • Henry L. Hudson

      Affiliations

    • Retina Centers, P.C., Tucson, Arizona
    • Corresponding Author InformationInquiries to Henry L. Hudson, 6585 North Oracle Road, Suite A, Tucson, AZ 85704
    • ,
  • R. Doyle Stulting

      Affiliations

    • Emory University Eye Center, Atlanta, Georgia
    • ,
  • Jeffrey S. Heier

      Affiliations

    • Ophthalmic Consultants of Boston, Boston, Massachusetts
    • ,
  • Stephen S. Lane

      Affiliations

    • Associated Eye Care, Stillwater, Minnesota
    • ,
  • David F. Chang

      Affiliations

    • Altos Eye Physicians, Los Altos, California
    • ,
  • Lawrence J. Singerman

      Affiliations

    • Retina Associates of Cleveland, Cleveland, Ohio
    • ,
  • Cynthia A. Bradford

      Affiliations

    • Dean A. McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
    • ,
  • Robert E. Leonard

      Affiliations

    • Dean A. McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
    • ,
  • IMT002 Study Group

,Accepted 1 July 2008.

References 

  1. Age-Related Eye Disease Study Research Group. Potential public health impact of age-related eye disease study results: AREDS Report No. 11. Arch Ophthalmol. 2003;121:1621–1624
  2. Owen CG, Fletcher AE, Donoghue M, et al. How big is the burden of visual loss caused by age-related macular degeneration in the United Kingdom?. Br J Ophthalmol. 2003;87:312–317
  3. Evans JR, Fletcher AE, Wormald RP. Age-related macular degeneration causing visual impairment in people 75 years or older in Britain. Ophthalmology. 2004;111:513–517
  4. Augood CA, Vingerling JR, de Jong PT, et al. Prevalence of age-related maculopathy in older Europeans: the European Eye Study. Arch Ophthalmol. 2006;124:529–535
  5. Jager RD, Mieler WF, Miller JW. Age-related macular degeneration. N Engl J Med. 2008;358:2606–2617
  6. Schein OD, Bressler NM, Price P. Photodynamic therapy with verteporfin: observations on the introduction of a new treatment into clinical practice. Arch Ophthalmol. 2005;123:58–63
  7. Wang JJ, Mitchell P, Smith W, Cumming RG. Bilateral involvement by age-related maculopathy lesions in a population. Br J Ophthalmol. 1998;82:743–747
  8. Brown MM, Brown GC, Sharma S, et al. The burden of age-related macular degeneration: a value-based analysis. Curr Opin Ophthalmol. 2006;17:257–266
  9. Brown GC, Sharma S, Brown MM, Kistler J. Utility values and age-related macular degeneration. Arch Ophthalmol. 2000;118:47–51
  10. Schmier JK, Halpern MT, Covert D, Delgado J, Sharma S. Impact of visual impairment on use of care giving by individuals with age-related macular degeneration. Retina. 2006;26:1056–1062
  11. Cahill MT, Banks AD, Stinnett SS, Toth CA. Vision-related quality of life in patients with bilateral severe age-related macular degeneration. Ophthalmology. 2005;112:152–158
  12. Hudson HL, Lane SS, Heier JS, et al. Implantable miniature telescope for the treatment of visual acuity loss resulting from end-stage age-related macular degeneration: 1-year results. Ophthalmology. 2006;113:1987–2001
  13. Submacular Surgery Trials (SST) Research Group. Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: quality-of-life findings: SST Report No. 12. Ophthalmology. 2004;111:1981–1992
  14. Hooper P, Jutai JW, Strong G, Russell-Minda E. Age-related macular degeneration and low-vision rehabilitation: a systematic review. Can J Ophthalmol. 2008;43:180–187
  15. Lane SS, Kuppermann BD, Fine IH, et al. A prospective multicenter trial to evaluate the safety and effectiveness of the implantable miniature telescope. Am J Ophthalmol. 2004;137:993–1001
  16. Chun DW, Heier JS, Raizman MB. Visual prosthetic device for bilateral end-stage macular degeneration. Expert Rev Med Devices. 2005;2:657–665
  17. Lane SS, Kuppermann BD. The implantable miniature telescope for macular degeneration. Curr Opin Ophthalmol. 2006;17:94–98
  18. Colby KA, Chang DF, Stulting RD, Lane SS. Surgical placement of an optical prosthetic device for end-stage macular degeneration: the implantable miniature telescope. Arch Ophthalmol. 2007;125:1118–1121
  19. Garfinkel RA, Berinstein DM, Frantz R. Treatment of choroidal neovascularization through the implantable miniature telescope. Am J Ophthalmol. 2006;141:766–767
  20. Levy JH, Pisacano AM. Clinical endothelial cell loss following phacoemulsification and silicone or polymethylmethacrylate lens implantation. J Cataract Refract Surg. 1988;14:299–302
  21. Liesegang TJ, Bourne WM, Ilstrup DM. Short- and long-term endothelial cell loss associated with cataract extraction and intraocular lens implantation. Am J Ophthalmol. 1984;97:32–39
  22. Richard J, Hoffart L, Chavane F, Ridings B, Conrath J. Corneal endothelial cell loss after cataract extraction by using ultrasound phacoemulsification versus a fluid-based system. Cornea. 2008;27:17–21
  23. Glasser DB, Matsuda M, Gager WE, Edelhauser HF. Corneal endothelial morphology after anterior chamber lens implantation. Arch Ophthalmol. 1985;103:1347–1349
  24. Edelhauser HF, Sanders DR, Azar R, Lamielle H. Corneal endothelial assessment after ICL implantation. J Cataract Refract Surg. 2004;30:576–583
  25. Azar RG, Holdbrook MJ, Lemp M, Edelhauser HF. Two-year corneal endothelial cell assessment following INTACS implantation. J Refract Surg. 2001;17:542–548
  26. Jones SS, Azar RG, Cristol SM, et al. Effects of laser in situ keratomileusis (LASIK) on the corneal endothelium. Am J Ophthalmol. 1998;125:465–471
  27. Collins MJ, Carr JD, Stulting RD, et al. Effect of laser in situ keratomileusis (LASIK) on the corneal endothelium three years postoperatively. Am J Ophthalmol. 2001;131:1–6
  28. Bourne WM, Nelson LR, Hodge DO. Continued endothelial cell loss ten years after lens implantation. Ophthalmology. 1994;101:1014–1023
  29. Submacular Surgery Trials Research Group. Evaluation of minimum clinically meaningful changes in scores on the National Eye Institute Visual Function Questionnaire (NEI-VFQ) SST Report No. 19. Ophthalmic Epidemiol. 2007;14:205–215
  30. Age-Related Eye Disease Study Research Group. Responsiveness of the National Eye Institute Visual Function Questionnaire to progression to advanced age-related macular degeneration, vision loss, and lens opacity: AREDS Report No. 14. Arch Ophthalmol. 2005;123:1207–1214
  31. Globe DR, Wu J, Azen SP, et al. The impact of visual impairment on self-reported visual functioning in Latinos (The Los Angeles Latino Eye Study). Ophthalmology. 2004;111:1141–1149
  32. Submacular Surgery Trials (SST) Research Group. Surgery for hemorrhagic choroidal neovascular lesions of age-related macular degeneration: quality-of-life findings (SST Report No. 14). Ophthalmology. 2004;111:2007–2014
  33. Klein BE, Klein R, Lee KE, Cruickshanks KJ. Performance-based and self-assessed measures of visual function as related to history of falls, hip fractures, and measured gait time (The Beaver Dam Eye Study). Ophthalmology. 1998;105:160–164
  34. Peli E. The optical functional advantages of an intraocular low-vision telescope. Optom Vis Sci. 2002;79:225–233
  35. Shuttleworth GN, Luhishi EA, Harrad RA. Do patients with age-related maculopathy and cataract benefit from cataract surgery?. Br J Ophthalmol. 1998;82:611–616

PII: S0002-9394(08)00523-0

doi: 10.1016/j.ajo.2008.07.003

American Journal of Ophthalmology
Volume 146, Issue 5 , Pages 664-673.e1 , November 2008

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