American Journal of Ophthalmology
Volume 146, Issue 6 , Pages 913-919 , December 2008

The Effect of Corneal Light Scatter on Vision After Penetrating Keratoplasty

  • Sanjay V. Patel

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota
    • Corresponding Author InformationInquiries to Sanjay V. Patel, Mayo Clinic, 200 First Street SW, Rochester, MN 55905
  • ,
  • Jay W. McLaren

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota
  • ,
  • David O. Hodge

      Affiliations

    • Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
  • ,
  • William M. Bourne

      Affiliations

    • Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota

,Accepted 9 July 2008.

References 

  1. Patel SV, Hodge DO, Bourne WM. Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty. Am J Ophthalmol. 2005;139:311–319
  2. Crawford GJ, Stulting RD, Waring GO, van Meter WS, Wilson LA. The triple procedure (Analysis of outcome, refraction, and intraocular lens power calculation). Ophthalmology. 1986;93:817–824
  3. Riddle HK, Parker DA, Price FW. Management of postkeratoplasty astigmatism. Curr Opin Ophthalmol. 1998;9:15–28
  4. Wilson SE, Bourne WM. Effect of recipient-donor trephine size disparity on refractive error in keratoconus. Ophthalmology. 1989;96:299–305
  5. Thompson RW, Price MO, Bowers PJ, Price J, Francis W. Long-term graft survival after penetrating keratoplasty. Ophthalmology. 2003;110:1396–1402
  6. Bell KD, Campbell RJ, Bourne WM. Pathology of late endothelial failure: late endothelial failure of penetrating keratoplasty: study with light and electron microscopy. Cornea. 2000;19:40–46
  7. Nishimura JK, Hodge DO, Bourne WM. Initial endothelial cell density and chronic endothelial cell loss rate in corneal transplants with late endothelial failure. Ophthalmology. 1999;106:1962–1965
  8. Patel SV, Winter EJ, McLaren JW, Bourne WM. Objective measurement of backscattered light from the anterior and posterior cornea in vivo. Invest Ophthalmol Vis Sci. 2007;48:166–172
  9. Lohmann CP, Timberlake GT, Fitzke FW, Gartry DS, Muir MK, Marshall J. Corneal light scattering after excimer laser photorefractive keratectomy: the objective measurements of haze. Refract Corneal Surg. 1992;8:114–121
  10. McLaren JW, Bourne WM. A new video pachometer. Invest Ophthalmol Vis Sci. 1999;40:1593–1598
  11. Van den Berg TJ. Importance of pathological intraocular light scatter for visual disability. Doc Ophthalmol. 1986;61:327–333
  12. Van den Berg TJ, IJspeert JK. Clinical assessment of intraocular stray light. Appl Opt. 1992;31:3694–3696
  13. Beck RW, Moke PS, Turpin AH, et al. A computerized method of visual acuity testing: adaptation of the Early Treatment of Diabetic Retinopathy Study testing protocol. Am J Ophthalmol. 2003;135:194–205
  14. Kitzmann AS, Winter EJ, Nau CB, McLaren JW, Hodge DO, Bourne WM. Comparison of corneal endothelial cell images from a noncontact specular microscope and a scanning confocal microscope. Cornea. 2005;24:980–984
  15. McLaren JW, Patel SV, Nau CB, Bourne WM. Automated assessment of keratocyte density in clinical confocal microscopy of the corneal stroma. J Microsc. 2008;229:21–31
  16. Patel SV, McLaren JW, Hodge DO, Bourne WM. Normal human keratocyte density and corneal thickness measurement by using confocal microscopy in vivo. Invest Ophthalmol Vis Sci. 2001;42:333–339
  17. Patel SV, Erie JC, McLaren JW, Bourne WM. Keratocyte density and recovery of subbasal nerves after penetrating keratoplasty and in late endothelial failure. Arch Ophthalmol. 2007;125:1693–1698
  18. Pesudovs K, Coster DJ. Assessment of visual function in cataract patients with a mean visual acuity of 6/9. Aust N Z J Ophthalmol. 1996;24:5–9
  19. Pesudovs K, Schoneveld P, Seto RJ, Coster DJ. Contrast and glare testing in keratoconus and after penetrating keratoplasty. Br J Ophthalmol. 2004;88:653–657
  20. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121–130
  21. Patel SV, McLaren JW, Hodge DO, Baratz KH. Scattered light and visual function in a randomized trial of deep lamellar endothelial keratoplasty and penetrating keratoplasty. Am J Ophthalmol. 2008;145:97–105
  22. Bourne WM, Brubaker RF. Decreased endothelial permeability in transplanted corneas. Am J Ophthalmol. 1983;96:362–367
  23. Feuk T, McQueen D. The angular dependence of light scattered from rabbit corneas. Invest Ophthalmol. 1971;10:294–299
  24. Freund DE, McCally RL, Farrell RA. Effects of fibril orientations on light scattering in the cornea. J Opt Soc Am A. 1986;3:1970–1982
  25. Freund DE, McCally RL, Farrell RA. Direct summation of fields for light scattering by fibrils with applications to normal cornea. Appl Opt. 1986;25:2739–2746
  26. Patel SV, Maguire LJ, McLaren JW, Hodge DO, Bourne WM. Femtosecond laser versus mechanical microkeratome: A randomized controlled study. Ophthalmology. 2007;114:1482–1490
  27. Netto MV, Mohan RR, Ambrosio R, Hutcheon AE, Zieske JD, Wilson SE. Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy. Cornea. 2005;24:509–522
  28. Lohmann CP, Gartry DS, Muir MK, Timberlake GT, Fitzke FW, Marshall J. Corneal haze after excimer laser refractive surgery: objective measurements and functional implications. Eur J Ophthalmol. 1991;1:173–180
  29. Pesudovs K, Coster DJ. Penetrating keratoplasty for keratoconus: the nexus between corneal wavefront aberrations and visual performance. J Refract Surg. 2006;22:926–931
  30. Price FW, Price MO. Descemet's stripping with endothelial keratoplasty in 200 eyes: Early challenges and techniques to enhance donor adherence. J Cataract Refr Surg. 2006;32:411–418
  31. Terry MA, Ousley PJ. Deep lamellar endothelial keratoplasty visual acuity, astigmatism, and endothelial survival in a large prospective series. Ophthalmology. 2005;112:1541–1548
  32. Price FW, Price MO. Endothelial keratoplasty to restore clarity to a failed penetrating graft. Cornea. 2006;25:895–899

PII: S0002-9394(08)00545-X

doi: 10.1016/j.ajo.2008.07.018

American Journal of Ophthalmology
Volume 146, Issue 6 , Pages 913-919 , December 2008