American Journal of Ophthalmology
Volume 147, Issue 3 , Pages 505-511.e1, March 2009

Visual Impairment and Its Impact on Health-related Quality of Life in Adolescents

  • Hwee-Bee Wong

      Affiliations

    • Health Services Research and Evaluation Division, Ministry of Health, Singapore, Republic of Singapore
    • Clinical Trials and Epidemiology Research Unit, Singapore, Republic of Singapore
    • Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, Republic of Singapore
    • Corresponding Author InformationInquiries to Hwee-Bee Wong, Health Services Research and Evaluation Division, Ministry of Health, 16 College Road, Singapore 169854, Republic of Singapore
  • ,
  • David Machin

      Affiliations

    • Clinical Trials and Epidemiology Research Unit, Singapore, Republic of Singapore
    • Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore, Republic of Singapore
    • Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, Sheffield, United Kingdom
  • ,
  • Say-Beng Tan

      Affiliations

    • Clinical Trials and Epidemiology Research Unit, Singapore, Republic of Singapore
    • Singapore Clinical Research Institute, Singapore, Republic of Singapore
    • Duke-National University of Singapore Graduate Medical School, Singapore, Republic of Singapore
  • ,
  • Tien-Yin Wong

      Affiliations

    • Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, Republic of Singapore
    • Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
    • Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore
  • ,
  • Seang-Mei Saw

      Affiliations

    • Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, Republic of Singapore
    • Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore

Accepted 18 September 2008. published online 04 December 2008.

Purpose

To determine the impact of visual impairment on health-related quality of life (QoL) measures in adolescents.

Design

School-based, cross-sectional study.

Methods

Adolescents aged 11 to 18 years from the Singapore Cohort Study of the Risk Factors for Myopia were analyzed. QoL scores were determined using parallel child-self and parent proxy-report of PedsQL 4.0 Generic Core Scales. Refractive error was measured using the table-mounted autorefractor (model RK5 Canon Inc, Ltd, Tochigiken, Japan) and habitual distance logarithm of the minimal angle of resolution (logMAR) visual acuity charts were used.

Results

Data on 1,249 adolescents and 948 parents were analyzed. The prevalence of better eye presenting visual impairment > 0.3 logMAR was 5.7%. The mean (standard deviation) total, physical, and psychosocial health scores of all adolescents were 83.6 (11.8), 89.9 (11.8), and 80.3 (13.7). Healthy adolescents with visual impairment reported statistically but not clinically lower total (−3.8; 95% confidence interval [CI], −7.1 to −0.5; P = .03), psychosocial (−4.2; 95% CI, −8.1 to −0.3; P = .03), and school functioning scores (−5.5, 95% CI, −10.2 to −0.9; P = .02) than those with normal vision. However, no significant difference was observed in the parent proxy-reported scores between the two groups. Differences in total scores between high (1.9; 95% CI, −0.6 to 4.4) and low-myopes (0.2; 95% CI, −1.3 to 1.6) compared with nonmyopes were not significant. Comparable scores were also reported by hyperopes, astigmatism, and their counterparts, as well as their parents. Concordance between child and parent proxy-report was < 0.07.

Conclusion

Healthy adolescents with visual impairment experienced statistically though not clinically impaired health related QoL, but refractive errors did not appear to have an impact on QoL.

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PII: S0002-9394(08)00752-6

doi:10.1016/j.ajo.2008.09.025

American Journal of Ophthalmology
Volume 147, Issue 3 , Pages 505-511.e1, March 2009