American Journal of Ophthalmology
Volume 148, Issue 1 , Pages 90-96.e2 , July 2009

Quantification of Error in Optical Coherence Tomography Central Macular Thickness Measurement in Wet Age-related Macular Degeneration

  • Nicola G. Ghazi

      Affiliations

    • Department of Ophthalmology, The University of Virginia Health System, Charlottesville, Virginia
    • Corresponding Author InformationInquiries to Nicola G. Ghazi, University of Virginia Health System, Department of Ophthalmology, P.O. Box 800715, Charlottesville, VA 22908
    • ,
  • Tyler Kirk

      Affiliations

    • Department of Ophthalmology, The University of Virginia Health System, Charlottesville, Virginia
    • ,
  • Souha Allam

      Affiliations

    • Department of Ophthalmology, The University of Virginia Health System, Charlottesville, Virginia
    • ,
  • Guofen Yan

      Affiliations

    • Department of Biostatistics, the University of Virginia Health System, Charlottesville, Virginia

,Accepted 10 February 2009.

References 

  1. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991;254:1178–1181
  2. Schuman JS, Puliafito CA, Fujimoto JG. Optical Coherence Tomography of Ocular Diseases. 2nd ed.. Thorofare, New Jersey: SLACK Inc; 2004;3–698
  3. Fung AE, Lalwani GA, Rosenfeld PJ, et al. An optical coherence tomography-guided, variable-dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am J Ophthalmol. 2007;143:566–583
  4. Ray R, Stinnett SS, Jaffe GJ. Evaluation of image artifact produced by optical coherence tomography of retinal pathology. Am J Ophthalmol. 2005;139:18–29
  5. Sadda SR, Wu Z, Walsh AC, et al. Errors in retinal thickness measurements obtained by optical coherence tomography. Ophthalmology. 2006;113:285–293
  6. Joeres S, Kaplowitz K, Brubaker JW, et al. Quantitative comparison of optical coherence tomography after pegaptanib or bevacizumab in neovascular age-related macular degeneration. Ophthalmology. 2008;115:347–354
  7. Strauss RW, Scholz F, Ulbig MW, Kampik A, Neubauer AS. Artifacts in optical coherence tomography (OCT) imaging of the retina. Klin Monatsbl Augenheilkd. 2007;224:47–51
  8. Patel PJ, Chen FK, Ikeji F, et al. Repeatability of stratus optical coherence tomography measures in neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:1084–1088
  9. Stein DM, Wollstein G, Ishikawa H, Hertzmark E, Noecker RJ, Schuman JS. Effect of corneal drying on optical coherence tomography. Ophthalmology. 2006;113:985–991
  10. Van Velthoven ME, van der Linden MH, de Smet MD, et al. Influence of cataract on optical coherence tomography image quality and retinal thickness. Br J Ophthalmol. 2006;90:1259–1262
  11. Savini G, Zanini M, Barboni P. Influence of pupil size and cataract on retinal nerve fiber layer thickness measurements by Stratus OCT. J Glaucoma. 2006;15:336–340
  12. Hougaard JL, Wang M, Sander B, Larsen M. Effects of pseudophakic lens capsule opacification on optical coherence tomography of the macula. Curr Eye Res. 2001;23:415–421
  13. Sadda SR, Joeres S, Wu Z, et al. Error correction and quantitative sub-analysis of optical coherence tomography data using computer-assisted grading. Invest Ophthalmol Vis Sci. 2007;48:839–848
  14. Koozekanani D, Boyer K, Roberts C. Retinal thickness measurements from optical coherence tomography using a Markov boundary model. IEEE Trans Med Imaging. 2001;20:900–916
  15. Ge J, Luo R, Guo Y. Corrective change of retinal thickness measured by optical coherence tomography and histologic studies. Yan Ke Xue Bao. 1999;15:153–155
  16. Leung CK, Chan WM, Chong KK, et al. Alignment artifacts in optical coherence tomography analyzed images. Ophthalmology. 2007;114:263–270

PII: S0002-9394(09)00114-7

doi: 10.1016/j.ajo.2009.02.017

American Journal of Ophthalmology
Volume 148, Issue 1 , Pages 90-96.e2 , July 2009

Article Tools

* Image Usage & Resolution