American Journal of Ophthalmology
Volume 148, Issue 1 , Pages 1-3 , July 2009

The As-Needed Treatment Strategy for Choroidal Neovascularization: A Feedback-Based Treatment System

  • Richard F. Spaide

      Affiliations

    • Corresponding Author InformationInquiries to Richard F. Spaide, 460 Park Ave, 5th Floor, New York, NY 10022

,Accepted 8 April 2009.

References 

  1. Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006;355:1419–1431
  2. Brown DM, Kaiser PK, Michels M, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med. 2006;355:1432–1444
  3. Fung AE, Lalwani GA, Rosenfeld PJ, et al. An optical coherence tomography-guided, variable-dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am J Ophthalmol. 2007;143:566–583
  4. Lalwani GA, Rosenfeld PJ, Fung AE, et al. A variable-dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration: year two of the PrONTO Study. Am J Ophthalmol. 2009;148:43–58
  5. Bashshur ZF, Haddad ZA, Schakal A, Jaafar RF, Saab M, Noureddin BN. Intravitreal bevacizumab for treatment of neovascular age-related macular degeneration: a one-year prospective study. Am J Ophthalmol. 2008;145:249–256
  6. Bashshur ZF, Haddad ZA, Schakal A, Jaafar RF, Saab M, Noureddin BN. Intravitreal bevacizumab for treatment of neovascular age-related macular degeneration: a one-year prospective study. Am J Ophthalmol. 2009;148:59–65
  7. Krohne TU, Eter N, Holz FG, Meyer CH. Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans. Am J Ophthalmol. 2008;146:508–512
  8. Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol. 2008;145:239–248
  9. Comparison of Age-related Macular Degeneration Treatments Trials (CATT): Lucentis—Avastin Trial. Manual of Procedures. http://www.med.upenn.edu/cpob/studies/documents/CATTMOPSept2008.pdfAccessed: April 7, 2009

 See accompanying Articles on pages 43 and 59.

PII: S0002-9394(09)00284-0

doi: 10.1016/j.ajo.2009.04.010

American Journal of Ophthalmology
Volume 148, Issue 1 , Pages 1-3 , July 2009

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