American Journal of Ophthalmology
Volume 148, Issue 5 , Pages 704-710.e2 , November 2009

Sympathetic Ophthalmia: Incidence of Ocular Complications and Vision Loss in the Sympathizing Eye

  • Anat Galor

      Affiliations

    • Bascom Palmer Eye Institute, University of Miami, Miami, Florida
  • ,
  • Janet L. Davis

      Affiliations

    • Bascom Palmer Eye Institute, University of Miami, Miami, Florida
  • ,
  • Harry W. Flynn Jr

      Affiliations

    • Bascom Palmer Eye Institute, University of Miami, Miami, Florida
    • Corresponding Author InformationInquiries to Harry W. Flynn, Jr, Bascom Palmer Eye Institute, 900 17th Street, Miami, FL 33136
  • ,
  • William J. Feuer

      Affiliations

    • Bascom Palmer Eye Institute, University of Miami, Miami, Florida
  • ,
  • Sander R. Dubovy

      Affiliations

    • Bascom Palmer Eye Institute, University of Miami, Miami, Florida
  • ,
  • Vikram Setlur

      Affiliations

    • Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois
  • ,
  • Muge R. Kesen

      Affiliations

    • Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois
  • ,
  • Debra A. Goldstein

      Affiliations

    • Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois
  • ,
  • Howard H. Tessler

      Affiliations

    • Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois
  • ,
  • Irina Bykhovskaya Ganelis

      Affiliations

    • Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland
  • ,
  • Douglas A. Jabs

      Affiliations

    • Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland
    • Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
  • ,
  • Jennifer E. Thorne

      Affiliations

    • Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland
    • Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland

,Accepted 27 May 2009.

References 

  1. Damico FM, Kiss S, Young LH. Sympathetic ophthalmia. Semin Ophthalmol. 2005;20:191–197
  2. Ahmad N, Soong TK, Salvi S, Rudle PA, Rennie IG. Sympathetic ophthalmia after ruthenium plaque brachytherapy. Br J Ophthalmol. 2007;91:399–401
  3. Buller AJ, Doris JP, Bonshek R, Brahma AK, Jones NP. Sympathetic ophthalmia following severe fungal keratitis. Eye. 2006;20:1306–1307
  4. Jonas JB, Back W, Sauder G, Junemann U, Harder B, Spandau UH. Sympathetic ophthalmia in vater association combined with persisting hyperplastic primary vitreous after cyclodestructive procedure. Eur J Ophthalmol. 2006;16:171–172
  5. Kilmartin DJ, Forrester JV, Dick AD. Cyclosporine-induced resolution of choroidal neovascularization associated with sympathetic ophthalmia. Arch Ophthalmol. 1998;116:249–250
  6. Makley TA, Azar A. Sympathetic ophthalmia (A long-term follow-up). Arch Ophthalmol. 1978;96:257–262
  7. Kilmartin DJ, Dick AD, Forrester JV. Prospective surveillance of sympathetic ophthalmia in the United Kingdom and Republic of Ireland. Br J Ophthalmol. 2000;84:259–263
  8. Lubin JR, Albert DM, Weinstein M. Sixty-five years of sympathetic ophthalmia (A clinicopathologic review of 105 cases (1913 to 1978)). Ophthalmology. 1980;87:109–121
  9. Marak GE. Recent advances in sympathetic ophthalmia. Surv Ophthalmol. 1979;24:141–156
  10. Jennings T, Tessler HH. Twenty cases of sympathetic ophthalmia. Br J Ophthalmol. 1989;73:140–145
  11. Reynard M, Riffenburgh RS, Maes EF. Effect of corticosteroid treatment and enucleation on the visual prognosis of sympathetic ophthalmia. Am J Ophthalmol. 1983;96:290–294
  12. Chan CC, Roberge RG, Whitcup SM, Nussenblatt RB. 32 cases of sympathetic ophthalmia (A retrospective study at the National Eye Institute, Bethesda, Maryland, from 1982 to 1992). Arch Ophthalmol. 1995;113:597–600
  13. Su DH, Chee SP. Sympathetic ophthalmia in Singapore: new trends in an old disease. Graefes Arch Clin Exp Ophthalmol. 2006;244:243–247
  14. Jabs DA. Improving the reporting of clinical case series. Am J Ophthalmol. 2005;139:900–905
  15. Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of uveitis nomenclature for reporting clinical data (Results of the First International Workshop). Am J Ophthalmol. 2005;140:509–516
  16. Machin D, Cheung Y, Parmer M. Survival analysis: A practical approach. 2nd edn.. Cambridge, United Kingdom: John Wiley & Sons; 2006;
  17. Hakin KN, Pearson RV, Lightman SL. Sympathetic ophthalmia: visual results with modern immunosuppressive therapy. Eye. 1992;6:453–455

 See accompanying Editorial on page 632.

PII: S0002-9394(09)00401-2

doi: 10.1016/j.ajo.2009.05.033

American Journal of Ophthalmology
Volume 148, Issue 5 , Pages 704-710.e2 , November 2009