American Journal of Ophthalmology
Volume 148, Issue 6 , Pages 818-819 , December 2009

Rationale for Radiotherapy in Thyroid Eye Disease

  • Julian D. Perry

      Affiliations

    • The Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, Ohio
    • Corresponding Author InformationInquiries to Julian D. Perry, The Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195
    • ,
  • Steven E. Feldon

      Affiliations

    • University of Rochester Eye Institute, Rochester, New York

,Accepted 23 July 2009.

References 

  1. Donaldson SS, Bagshaw MA, Kriss JP. Supervoltage orbital radiotherapy for Graves' ophthalmopathy. J Clin Endocrinol Metab. 1973;37:276–285
  2. Teng CS, Crombie AL, Hall R, Ross WM. An evaluation of supervoltage orbital irradiation for Graves' ophthalmopathy. Clin Endocrinol. 1980;13:545–551
  3. Hurbli T, Char DH, Harris J, et al. Radiation therapy for thyroid eye diseases. Am J Ophthalmol. 1985;99:633–637
  4. Prummel MF, Mourits MP, Blank L, et al. Randomized double-blind trial of prednisone versus radiotherapy in Graves' ophthalmopathy. Lancet. 1993;342:949–954
  5. Mourits MP, Van Kempen-Harteveld ML, Garcia MB, et al. Radiotherapy for Graves' orbitopathy: randomized placebo-controlled study. Lancet. 2000;355:1505–1509
  6. Ohtsuka K, Sato A, Kawaguchi S, et al. Effect of steroid pulse therapy with and without orbital radiotherapy on Graves' ophthalmopathy. Am J Ophthalmol. 2003;135:285–290
  7. Prummel MF, Terwee CB, Gerding MN, et al. A randomized controlled trial of orbital radiotherapy versus sham irradiation in patients with mild Graves' ophthalmopathy. J Clin Endocrinol Metab. 2004;89:15–20
  8. Feldon SE. Radiation therapy for Graves' ophthalmopathy: trick or treat?. Ophthalmology. 2001;108:1521–1522
  9. Gorman CA, Garrity JA, Fatourechi V, et al. A prospective, randomized, double-blind, placebo-controlled study of orbital radiotherapy for Graves' ophthalmopathy. Ophthalmology. 2001;108:1523–1534
  10. Bradley EA, Gower EW, Bradley DJ, et al. Orbital radiation for Graves ophthalmopathy: a report by the American Academy of Ophthalmology. Ophthalmology. 2008;115:398–409
  11. Guy JR, Fagien S, Donovan JP, Rubin ML. Methylprednisolone pulse therapy in severe dysthyroid optic neuropathy. Ophthalmology. 1989;96:1048–1052
  12. Perry JD, Foster JA, Kadakia A. Transcaruncular orbital decompression for treatment of dysthyroid compressive optic neuropathy. Ophthalmic Plast Reconst Surg. 2003;19:353–358
  13. Kuriyan AE, Phipps RP, O'Loughlin CW, Feldon SE. Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxib. Thyroid. 2008;18:911–914

PII: S0002-9394(09)00546-7

doi: 10.1016/j.ajo.2009.07.034

American Journal of Ophthalmology
Volume 148, Issue 6 , Pages 818-819 , December 2009

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