American Journal of Ophthalmology
Volume 149, Issue 1 , Pages 70-76.e2 , January 2010

Management of Iris Melanomas With 125Iodine Plaque Radiotherapy

  • Bruno F. Fernandes

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationInquiries to Bruno F. Fernandes, 600 University Street, Room 18-706, Toronto, ON M5G-2M9, Canada
    • ,
  • Hatem Krema

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Emiliano Fulda

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Charles J. Pavlin

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • David G. Payne

      Affiliations

    • Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Hugh D. McGowan

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Ernest Rand Simpson

      Affiliations

    • Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

,Accepted 6 August 2009.

References 

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  2. Raivio I. Uveal melanoma in Finland (An epidemiological, clinical, histological, and prognostic study). Acta Ophthalmol Suppl. 1977;1–64
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  5. Territo C, Shields CL, Shields JA, Augsburger JJ, Schroeder RP. Natural course of melanocytic tumors of the iris. Ophthalmology. 1988;95:1251–1255
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  7. Conway RM, Chew T, Golchet P, Desai K, Lin S, O'Brien J. Ultrasound biomicroscopy: role in diagnosis and management in 130 consecutive patients evaluated for anterior segment tumours. Br J Ophthalmol. 2005;89:950–955
  8. Damato B, Kacperek A, Chopra M, Sheen MA, Campbell IR, Errington RD. Proton beam radiotherapy of iris melanoma. Int J Radiat Oncol Biol Phys. 2005;63:109–115
  9. Rundle P, Singh AD, Rennie I. Proton beam therapy for iris melanoma: a review of 15 cases. Eye. 2007;21:79–82
  10. Shields CL, Naseripour M, Shields JA, Freire J, Cater J. Custom-designed plaque radiotherapy for nonresectable iris melanoma in 38 patients: tumor control and ocular complications. Am J Ophthalmol. 2003;135:648–656
  11. Finger PT, Reddy S, Chin K. High-frequency ultrasound characteristics of 24 iris and iridociliary melanomas: before and after plaque brachytherapy. Arch Ophthalmol. 2007;125:1051–1058
  12. Conway RM, Chua WC, Qureshi C, Billson FA. Primary iris melanoma: diagnostic features and outcome of conservative surgical treatment. Br J Ophthalmol. 2001;85:848–854
  13. Naumann GO, Rummelt V. Block excision of tumors of the anterior uvea (Report on 68 consecutive patients). Ophthalmology. 1996;103:2017–2027discussion 2027–2028
  14. Workman DM, Weiner JW. Melanocytic lesions of the iris—a clinicopathological study of 100 cases. Aust N Z J Ophthalmol. 1990;18:381–384
  15. Geisse LJ, Robertson DM. Iris melanomas. Am J Ophthalmol. 1985;99:638–648
  16. Marigo FA, Finger PT. Anterior segment tumors: current concepts and innovations. Surv Ophthalmol. 2003;48:569–593
  17. Marigo FA, Finger PT, McCormick SA, et al. Iris and ciliary body melanomas: ultrasound biomicroscopy with histopathologic correlation. Arch Ophthalmol. 2000;118:1515–1521

PII: S0002-9394(09)00569-8

doi: 10.1016/j.ajo.2009.08.007

American Journal of Ophthalmology
Volume 149, Issue 1 , Pages 70-76.e2 , January 2010

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