American Journal of Ophthalmology
Volume 149, Issue 3 , Pages 390-397.e1 , March 2010

Complications and Clinical Outcomes of Descemet Stripping Automated Endothelial Keratoplasty With Intraocular Lens Exchange

  • Anand K. Shah

      Affiliations

    • Devers Eye Institute, Portland, Oregon
    • Corresponding Author InformationInquiries to Anand K. Shah, Devers Eye Institute, 1040 NW 22nd Avenue, Portland, OR 97210
  • ,
  • Mark A. Terry

      Affiliations

    • Devers Eye Institute, Portland, Oregon
    • Lions Vision Research Laboratory of Oregon, Portland, Oregon
  • ,
  • Neda Shamie

      Affiliations

    • Devers Eye Institute, Portland, Oregon
  • ,
  • Edwin S. Chen

      Affiliations

    • Devers Eye Institute, Portland, Oregon
  • ,
  • Paul M. Phillips

      Affiliations

    • Devers Eye Institute, Portland, Oregon
  • ,
  • Karen L. Hoar

      Affiliations

    • Devers Eye Institute, Portland, Oregon
  • ,
  • Daniel J. Friend

      Affiliations

    • Devers Eye Institute, Portland, Oregon
    • Lions Vision Research Laboratory of Oregon, Portland, Oregon
  • ,
  • David Davis-Boozer

      Affiliations

    • Devers Eye Institute, Portland, Oregon
    • Lions Vision Research Laboratory of Oregon, Portland, Oregon

,Accepted 1 November 2009.

References 

  1. Terry MA. Endothelial keratoplasty: history, current state, and future directions. Cornea. 2006;25:873–878
  2. Melles GR, Eggink FA, Lander F, et al. A surgical technique for posterior lamellar keratoplasty. Cornea. 1998;17:618–626
  3. Terry MA, Ousley PJ. Endothelial replacement without surface corneal incisions or sutures: topography of the deep lamellar endothelial keratoplasty procedure. Cornea. 2001;20:14–18
  4. Terry MA. A new approach for endothelial transplantation: deep lamellar endothelial keratoplasty. Int Ophthalmol Clin. 2003;43:183–193
  5. Melles GR, Lander F, Beekhuis WH, Remeijer L, Binder PS. Posterior lamellar keratoplasty for a case of pseudophakic bullous keratopathy. Am J Ophthalmol. 1999;127:340–341
  6. Terry MA, Ousley PJ. Deep lamellar endothelial keratoplasty in the first United States patients: early clinical results. Cornea. 2001;20:239–243
  7. Terry MA. Endothelial replacement: the limbal pocket approach. Ophthalmol Clin North Am. 2003;16:103–112
  8. Terry MA, Ousley PJ. In pursuit of emmetropia: spherical equivalent refraction results with deep lamellar endothelial keratoplasty (DLEK). Cornea. 2003;22:619–626
  9. Terry MA, Ousley PJ. Replacing the endothelium without corneal surface incisions or sutures: the first United States clinical series using the deep lamellar endothelial keratoplasty procedure. Ophthalmology. 2003;110:755–764discussion 764
  10. Terry MA, Ousley PJ. Rapid visual rehabilitation after endothelial transplants with deep lamellar endothelial keratoplasty (DLEK). Cornea. 2004;23:143–153
  11. Terry MA, Ousley PJ. Deep lamellar endothelial keratoplasty visual acuity, astigmatism, and endothelial survival in a large prospective series. Ophthalmology. 2005;112:1541–1548
  12. Terry MA, Ousley PJ. Small-incision deep lamellar endothelial keratoplasty (DLEK): six-month results in the first prospective clinical study. Cornea. 2005;24:59–65
  13. Terry MA. Endothelial keratoplasty: clinical outcomes in the two years following deep lamellar endothelial keratoplasty (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2007;105:530–563
  14. Terry MA, Wall JM, Hoar KL, Ousley PJ. A prospective study of endothelial cell loss during the 2 years after deep lamellar endothelial keratoplasty. Ophthalmology. 2007;114:631–639
  15. Melles GR, Wijdh RH, Nieuwendaal CP. A technique to excise the Descemet membrane from a recipient cornea (descemetorhexis). Cornea. 2004;23:286–288
  16. Price FW, Price MO. Endothelial keratoplasty to restore clarity to a failed penetrating graft. Cornea. 2006;25:895–899
  17. Price FW, Price MO. Descemet's stripping with endothelial keratoplasty in 200 eyes: early challenges and techniques to enhance donor adherence. J Cataract Refract Surg. 2006;32:411–418
  18. Price MO, Price FW. Descemet's stripping with endothelial keratoplasty: comparative outcomes with microkeratome-dissected and manually dissected donor tissue. Ophthalmology. 2006;113:1936–1942
  19. Price FW, Price MO. Descemet's stripping with endothelial keratoplasty in 50 eyes: a refractive neutral corneal transplant. J Refract Surg. 2005;21:339–345
  20. Nieuwendaal CP, Lapid-Gortzak R, van der Meulen IJ, Melles GJ. Posterior lamellar keratoplasty using descemetorhexis and organ-cultured donor corneal tissue (Melles technique). Cornea. 2006;25:933–936
  21. Gorovoy MS. Descemet-stripping automated endothelial keratoplasty. Cornea. 2006;25:886–889
  22. Chen ES, Terry MA, Shamie N, Hoar KL, Friend DJ. Descemet-stripping automated endothelial keratoplasty: six-month results in a prospective study of 100 eyes. Cornea. 2008;27:514–520
  23. Terry MA, Shamie N, Chen ES, Hoar KL, Friend DJ. Endothelial keratoplasty: a simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block. Ophthalmology. 2008;115:1179–1186
  24. Koenig SB, Covert DJ. Early results of small-incision Descemet's stripping and automated endothelial keratoplasty. Ophthalmology. 2007;114:221–226
  25. Terry MA, Chen ES, Shamie N, Hoar KL, Friend DJ. Endothelial cell loss after Descemet's stripping endothelial keratoplasty in a large prospective series. Ophthalmology. 2008;115:488–496e3
  26. Terry MA, Shamie N, Chen ES, Hoar KL, Phillips PM, Friend DJ. Endothelial keratoplasty: the influence of pre-operative donor endothelial cell densities on dislocations, primary graft failure and one year cell counts. Cornea. 2008;27:1131–1137
  27. Suh LH, Yoo SH, Deobhakta A, et al. Complications of Descemet's stripping with automated endothelial keratoplasty: survey of 118 eyes at one institute. Ophthalmology. 2008;115:1517–1524
  28. Price MO, Price FW. Descemet's stripping endothelial keratoplasty. Curr Opin Ophthalmol. 2007;18:290–294
  29. Price MO, Baig KM, Brubaker JW, Price FW. Randomized, prospective comparison of precut vs surgeon-dissected grafts for Descemet stripping automated endothelial keratoplasty. Am J Ophthalmol. 2008;146:36–41
  30. Mearza AA, Qureshi MA, Rostron CK. Experience and 12-month results of Descemet-stripping endothelial keratoplasty (DSEK) with a small-incision technique. Cornea. 2007;26:279–283
  31. Terry MA, Shamie N, Chen ES, et al. Endothelial keratoplasty for Fuchs' dystrophy with cataract: complications and clinical results with the new triple procedure. Ophthalmology. 2009;116:631–639
  32. Wylegala E, Tarnawska D. Management of pseudophakic bullous keratopathy by combined Descemet-stripping endothelial keratoplasty and intraocular lens exchange. J Cataract Refract Surg. 2008;34:1708–1714
  33. Cosar CB, Sridhar MS, Cohen EJ, et al. Indications for penetrating keratoplasty and associated procedures, 1996–2000. Cornea. 2002;21:148–151
  34. Chang JH, Lee JH. Long-term results of implantation of posterior chamber intraocular lens bysuture fixation. Korean J Ophthalmol. 1991;5:42–46
  35. Djalilian AR, Anderson SO, Fang-Zen M, Lane SS, Holland EJ. Long-term results of transsclerally sutured posterior chamber lenses in penetrating keratoplasty. Cornea. 1998;17:359–364
  36. Holland EJ, Daya SM, Evangelista A, et al. Penetrating keratoplasty and transscleral fixation of posterior chamber lens. Am J Ophthalmol. 1992;114:182–187
  37. van der Schaft Tl, van Rij G, Renardel de Lavalette JG, Beekhuis WH. Results of penetrating keratoplasty for pseudophakic bullous keratopathy with the exchange of an intraocular lens. Br J Ophthalmol. 1989;73:704–708
  38. Allan BD, Terry MA, Price FW, Price MO, Griffin NB, Claesson M. Corneal transplant rejection rate and severity after endothelial keratoplasty. Cornea. 2007;26:1039–1042
  39. Groat B, Ying MS, Vroman DT, Fernandez de Castro LE. Descemet-stripping automated endothelial keratoplasty technique in patients with anterior chamber intraocular lenses [video report]. Br J Ophthalmol. 2007;91:714
  40. Chen ES, Terry MA, Shamie N, Phillips PM, Friend DJ. Retention of an anterior chamber IOL versus IOL exchange in endothelial keratoplasty. J Cataract Refract Surg. 2009;35:613
  41. O'Brien PD, Lake DB, Saw VP, Rostron CK, Dart JK, Allan BD. Endothelial keratoplasty: case selection in the learning curve. Cornea. 2008;27:1114–1118
  42. Lake DB, Rostron CK. Management of angle-supported intraocular lens and iridectomy in Descemet-stripping endothelial keratoplasty. Cornea. 2008;27:223–224
  43. Terry MA, Saad HA, Shamie N, et al. Endothelial keratoplasty: the influence of insertion techniques and incision size on donor endothelial survival. Cornea. 2009;28:24–31
  44. Terry MA. Pre-cut tissue for Descemet stripping automated endothelial keratoplasty: complications are from technique, not tissue. [editorial] Cornea. 2008;6:627–629

PII: S0002-9394(09)00804-6

doi: 10.1016/j.ajo.2009.11.002

American Journal of Ophthalmology
Volume 149, Issue 3 , Pages 390-397.e1 , March 2010