American Journal of Ophthalmology
Volume 149, Issue 5 , Pages 735-740 , May 2010

Ocular Risk Factors for Age-Related Macular Degeneration: The Los Angeles Latino Eye Study

  • Samantha Fraser-Bell

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
    • Department of Ophthalmology, University of Sydney, New South Wales, Australia
    • ,
  • Farzana Choudhury

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
    • ,
  • Ronald Klein

      Affiliations

    • Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • ,
  • Stanley Azen

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
    • Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
    • ,
  • Rohit Varma

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California
    • Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California
    • Corresponding Author InformationInquiries to Rohit Varma, Doheny Eye Institute, Suite 4900, 1450 San Pablo St, Los Angeles, CA 90033
    • ,
  • Los Angeles Latino Eye Study Group

      Affiliations

    • Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California

,Accepted 6 November 2009.

References 

  1. Klein R, Wang Q, Klein BE, et al. The relationship of age-related maculopathy, cataract, and glaucoma to visual acuity. Invest Ophthalmol Vis Sci. 1995;36:182–191
  2. Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol. 2004;122:564–572
  3. National Advisory Eye Council. Vision research: a national plan 1994-1998. In: Bethesda, MD: National Eye Institute, National Institutes of Health; 1993;p. 305–321
  4. Ikram MK, van Leeuwen R, Vingerling JR, et al. Relationship between refraction and prevalent as well as incident age-related maculopathy: the Rotterdam Study. Invest Ophthalmol Vis Sci. 2003;44:3778–3782
  5. Wang JJ, Mitchell P, Smith W. Refractive error and age-related maculopathy: the Blue Mountains Eye Study. Invest Ophthalmol Vis Sci. 1998;39:2167–2171
  6. Klein R, Klein BE, Wang Q, Moss SE. Is age-related maculopathy associated with cataracts?. Arch Ophthalmol. 1994;112:191–196
  7. Mitchell P, Smith W, Wang JJ. Iris color, skin sun sensitivity, and age-related maculopathy (The Blue Mountains Eye Study). Ophthalmology. 1998;105:1359–1363
  8. Wang JJ, Klein R, Smith W, et al. Cataract surgery and the 5-year incidence of late-stage age-related maculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies. Ophthalmology. 2003;110:1960–1967
  9. Freeman EE, Munoz B, West SK, et al. Is there an association between cataract surgery and age-related macular degeneration? (Data from three population-based studies). Am J Ophthalmol. 2003;135:849–856
  10. Varma R, Paz SH, Azen SP, et al. The Los Angeles Latino Eye Study: design, methods, and baseline data. Ophthalmology. 2004;111:1121–1131
  11. Varma R, Fraser-Bell S, Tan S, et al. Prevalence of age-related macular degeneration in Latinos: the Los Angeles Latino eye study. Ophthalmology. 2004;111:1288–1297
  12. Klein R, Davis MD, Magli YL, et al. The Wisconsin age-related maculopathy grading system. Ophthalmology. 1991;98:1128–1134
  13. Klein R, Klein BE, Linton KL. Prevalence of age-related maculopathy (The Beaver Dam Eye Study). Ophthalmology. 1992;99:933–943
  14. Seddon JM, Sahagian CR, Glynn RJ, et al. Evaluation of an iris color classification system (The Eye Disorders Case-Control Study Group). Invest Ophthalmol Vis Sci. 1990;31:1592–1598
  15. Chylack LT, Leske MC, Sperduto R, et al. Lens Opacities Classification System. Arch Ophthalmol. 1988;106:330–334
  16. Ferris FL, Bailey I. Standardizing the measurement of visual acuity for clinical research studies: Guidelines from the Eye Care Technology Forum. Ophthalmology. 1996;103:181–182
  17. Klein R, Klein BEK, Jensen SC, Meuer SM. The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study. Ophthalmology. 1997;104:7–21
  18. Klein R, Klein BE, Wong TY, et al. The association of cataract and cataract surgery with the long-term incidence of age-related maculopathy: the Beaver Dam eye study. Arch Ophthalmol. 2002;120:1551–1558
  19. Cugati S, Mitchell P, Rochtchina E, et al. Cataract surgery and the 10-year incidence of age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology. 2006;113:2020–2025
  20. Ho L, Boekhoorn SS, Liana , et al. Cataract surgery and the risk of aging macula disorder: the Rotterdam Study. Invest Ophthalmol Vis Sci. 2008;49(11):4795–4800
  21. Pham TQ, Cugati S, Rochtchina E, et al. Early age-related maculopathy in eyes after cataract surgery. Eye. 2007;21(4):512–517
  22. Eye Disease Case-Control Study Group. Risk factors for neovascular age-related macular degeneration. Arch Ophthalmol. 1992;110:1701–1708
  23. Hyman LG, Lilienfeld AM, Ferris FL, Fine SL. Senile macular degeneration: a case-control study. Am J Epidemiol. 1983;118:213–227
  24. Chaine G, Hullo A, Sahel J, et al. Case-control study of the risk factors for age related macular degeneration (France-DMLA Study Group). Br J Ophthalmol. 1998;82:996–1002
  25. Xu L, Li Y, Zheng Y, Jonas JB. Associated factors for age related maculopathy in adult population in China: Beijing eye study. Br. J. Opthalmol. 2006;90;:1087–1090
  26. Friedman E, Ivry M, Ebert E, et al. Increased scleral rigidity and age-related macular degeneration. Ophthalmology. 1989;96:104–108
  27. Schachat AP, Hyman L, Leske MC, et al. Features of age-related macular degeneration in a black population (The Barbados Eye Study Group). Arch Ophthalmol. 1995;113:728–735
  28. Munoz B, West SK, Rubin GS, et al. Causes of blindness and visual impairment in a population of older Americans: The Salisbury Eye Evaluation Study. Arch Ophthalmol. 2000;118:819–825
  29. Klein BE, Klein R. Cataracts and macular degeneration in older Americans. Arch Ophthalmol. 1982;100:571–573
  30. Klein R, Rowland ML, Harris MI. Racial/ethnic differences in age-related maculopathy (Third National Health and Nutrition Examination Survey). Ophthalmology. 1995;102:371–381
  31. Cruickshanks KJ, Hamman RF, Klein R, et al. The prevalence of age-related maculopathy by geographic region and ethnicity (The Colorado-Wisconsin Study of Age-Related Maculopathy). Arch Ophthalmol. 1997;115:242–250
  32. Holz FG, Piguet B, Minassian DC, et al. Decreasing stromal iris pigmentation as a risk factor for age-related macular degeneration. Am J Ophthalmol. 1994;117:19–23
  33. Weiter JJ, Delori CD, Wing GL, Fitch KA. Relationship of senile macular degeneration to ocular pigmentation. Am J Ophthalmol. 1985;99:185–187
  34. Sandberg MA, Gaudio AR, Miller S, Weiner A. Iris pigmentation and extent of disease in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 1994;35:2734–2740
  35. Jampol LM, Tielsch J. Race, macular degeneration, and the Macular Photocoagulation Study. Arch Ophthalmol. 1992;110:1699–1700
  36. Blumenkranz M, Russell S, Robey M, et al. Risk factors in age related maculopathy complicated by choroidal neovascularisation. Ophthalmology. 1986;93:552–558
  37. West SK, Rosenthal FS, Bressler NM, et al. Exposure to sunlight and other risk factors for age-related macular degeneration. Arch Ophthalmol. 1989;107:875–879
  38. Vinding T. Pigmentation of the eye and hair in relation to age-related macular degeneration (An epidemiological study of 1000 aged individuals). Acta Ophthalmol Copenh. 1990;68:53–58

PII: S0002-9394(09)00876-9

doi: 10.1016/j.ajo.2009.11.013

American Journal of Ophthalmology
Volume 149, Issue 5 , Pages 735-740 , May 2010

Article Tools