Corneal Aberrations and Visual Acuity After Laser In Situ Keratomileusis: Femtosecond Laser Versus Mechanical Microkeratome
Accepted 12 December 2009. published online 15 March 2010.
Purpose
To compare corneal high-order aberrations and visual acuity after laser in situ keratomileusis (LASIK) with the flap created by a femtosecond laser (bladeless) to LASIK with the flap created by a mechanical microkeratome.
Design
Prospective, randomized, paired-eye study.
Methods
Fellow eyes of 21 patients with myopia or myopic astigmatism were randomized by ocular dominance. Corneal topography and visual acuity were measured before and at 1, 3, 6, 12, and 36 months after LASIK. Wavefront errors from the anterior corneal surface were calculated from the topography data over 4- and 6-mm-diameter pupils and decomposed into Zernike polynomials to the 6th order.
Results
There were no differences in corneal total high-order aberrations, spherical aberration, coma, or trefoil between methods of flap creation at any examination over 4- and 6-mm-diameter pupils. Over a 6-mm pupil, total high-order aberrations increased by 1 month after LASIK with both treatments (P ≤ .001) and remained increased through 36 months (P ≤ .001). Uncorrected and best-corrected visual acuity did not differ between methods at any examination and remained stable postoperatively through 3 years; the minimum detectable difference in visual acuity between treatments was ≤0.1 logMAR (≤1 line of vision, α = 0.05/6, β = 0.20, n = 21).
Conclusions
The planar configuration of the femtosecond laser flap did not offer any advantage in corneal high-order aberrations or visual acuity through 3 years after LASIK. Corneal high-order aberrations remain stable through 3 years after LASIK.
aDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota
bDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
Inquiries to Sanjay V. Patel, Department of Ophthalmology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
ABSTRACT