Purpose
To investigate the retinal and choroidal changes using spectral-domain optical coherence
tomography (SD OCT) and to identify factors associated with visual outcome in eyes
with central retinal artery occlusion (CRAO).
Design
Retrospective, observational case series.
Methods
setting: Institutional. patients: A total of 134 eyes diagnosed with acute (symptom onset ≤ 7 days) nonarteritic CRAO
examined with SD OCT at baseline and follow-up visits. observations: Based on funduscopic and angiographic findings, CRAO was categorized into 3 stages:
incomplete, subtotal, and total. Abnormal morphologic features were evaluated from
SD OCT images. Central macular thickness (CMT), inner and outer retinal thicknesses,
and subfoveal choroidal thickness (SFCT) were measured. The clinical and SD OCT features
were correlated with the final best-corrected visual acuities (BCVA). main outcome measures: Retinal and choroidal thickness and BCVA.
Results
Features of SD OCT at the initial presentation included inner and outer retinal thickening.
At baseline, the frequency of inner and outer retinal thickening and macular edema
(CMT > 300 μm) differed significantly among CRAO stages (all P < .05). SFCT in eyes with total CRAO was significantly thinner compared with that
of the contralateral eyes (P = .009). A higher CRAO stage was associated significantly with macular edema at baseline
(P < .001) and retinal thinning at the final visit (P = .010). Baseline CMT was correlated significantly with final BCVA (P < .001). Multivariate logistic regression analyses revealed that severe vision loss
(BCVA < 20/200) was associated significantly with CRAO stage (P < .001) and baseline CMT (P = .005).
Conclusions
CRAO resulted in inner and outer retinal thickening in the acute stages and subsequent
atrophic changes in the inner and outer retina. SD OCT may be a useful noninvasive
imaging tool for diagnosis, staging, and prognosis of CRAO.
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Biography
Seong Joon Ahn, MD, is a retina specialist at Armed Forces Capital Hospital, Seongnam, South Korea. Dr. Ahn received his MD from Seoul National University College of Medicine in 2007. He completed a residency in ophthalmology at Seoul National University Hospital in 2012. His current research of interests includes fields of retina.
Article Info
Publication History
Published online: January 08, 2015
Accepted:
January 1,
2015
Identification
Copyright
© 2015 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
